Summary of Clinical Use

Bentracimab is an advanced clinical candidate, with evidence of efficacy as a ticagrelor reversal agent [1,3-4].

Clinical Trials
Clinical Trial ID	Title	Type	Source	Comment	References
NCT03928353	Study to Evaluate the Safety, Tolerability, PK and PD of PB2452 in Healthy Younger, Older and Elderly Subjects	Phase 2 Interventional	SFJ Pharmaceuticals, Inc.
NCT04122170	Phase 2B Study to Evaluate the Efficacy of Bentracimab (PB2452) in Reversal of Ticagrelor in Subjects Aged 50-80 Years Old	Phase 2 Interventional	SFJ Pharmaceuticals, Inc.
NCT04286438	Bentracimab in Ticagrelor-treated Patients With Uncontrolled Bleeding or Requiring Urgent Surgery or Invasive Procedure	Phase 3 Interventional	SFJ Pharmaceuticals, Inc.