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vutrisiran   Click here for help

GtoPdb Ligand ID: 13616

Synonyms: ALN-65492 | ALN-TTRSC02 | Amvuttra® | votrisiran
Approved drug
vutrisiran is an approved drug (EMA, FDA & UK MHRA (2022))
Compound class: Nucleic acid
Comment: Vutrisiran (ALN-65492) is a GalNAc conjugated double-stranded small interfering ribonucleic acid (siRNA) drug. It acts as a transthyretin (TTR) synthesis inhibitor.
We have been unable to locate a full chemical SMILES for the drug, or its HELM notation.
Classification Click here for help
Compound class Nucleic acid
Compound subclass siRNA
Target transthyretin (TTR) mRNA
Approved drug? Yes. UK MHRA (2022)  |  EU EMA (2022)  |  US FDA (2022)
International Nonproprietary Names Click here for help
INN number INN
10579 vutrisiran
Synonyms Click here for help
ALN-65492 | ALN-TTRSC02 | Amvuttra® | votrisiran
Database Links Click here for help
CAS Registry No. 1867157-35-4 (source: WHO INN record)
ChEMBL Ligand CHEMBL4594511
DrugBank Ligand DB16699
GtoPdb PubChem SID 504705435
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