QM107   Click here for help

GtoPdb Ligand ID: 13527

Compound class: Peptide
Comment: QM107 is a synthetic short peptide that mimics the CD148-binding domain of human syndecan 2 (SDC2; P34741). It was designed to activate CD148 phosphatase activity as a mechanism to inhibit pro-angiogenic signalling as a novel treatment for neovascular age-related macular degeneration.
Selectivity at catalytic receptors
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
RTP Type J Hs Activator Binding - - -