Synonyms: AMG-191 | AMG191 | JSP-191 | JSP191
Compound class:
Antibody
Comment: Briquilimab (JSP191) is a chimeric humanized monoclonal antibody that targets KIT proto-oncogene receptor tyrosine kinase.
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References |
1. Jung D, Long-Boyle JR, Pang WW, Gobburu JVS. (2024)
Pharmacokinetics of Briquilimab as a Conditioning Agent for Hematopoietic Stem Cell Transplantation in Patients With Severe Combined Immunodeficiency, Myelodysplastic Syndrome, or Acute Myeloid Leukemia. Transplant Cell Ther, 30 (9): 923.e1-923.e9. [PMID:38972509] |
2. Wedi B. (2023)
Inhibition of KIT for chronic urticaria: a status update on drugs in early clinical development. Expert Opin Investig Drugs, 32 (11): 1043-1054. [PMID:37897679] |