HLX22   Click here for help

GtoPdb Ligand ID: 13443

Compound class: Antibody
Comment: HLX22 is a humanized anti-HER2 (EGFR2; ERBB2) IgG1 monoclonal antibody. It binds within the same HER2 subdomain as trastuzumab, but at a separate, non-overlapping epitope [1]. HLX22 is proposed to offer synergistic antitumour efficacy in combination with trastuzumab/trastuzumab biosimilars.
Selectivity at catalytic receptors
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
erb-b2 receptor tyrosine kinase 2 Hs Antibody Inhibition - - - 1
⤷ [1]