NN1213 
GtoPdb Ligand ID: 13441
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Synonyms: NN-1213 | peptide 21 [PMID: 38960379]
Compound class:
Peptide
Comment: NN1213 is a synthetic human amylin analogue [1]. It is conjugated with a fatty acid (at Lys1) to improve its chemical stability and circulating half-life. NN1213 was selected for selectivity for AMY3 receptor compared to the calcitonin receptor. Amylin analogues have appetite suppressing action that has potential as a weight management strategy in the clinic.
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
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