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ordesekimab   Click here for help

GtoPdb Ligand ID: 13046

Synonyms: AMG-714 | AMG714 | MAb146B7 | PRV-015
Immunopharmacology Ligand
Compound class: Antibody
Comment: Ordesekimab (AMG714, formerly PRV-015) is a fully human anti-IL-15 monoclonal antibody [1]. It binds to Il-15-IL-15Rα complexes on monocytes and disrupts interaction of the cytokine-bound receptor α subunit with the IL-2Rβ and common γ chains of the IL-15 receptor complex that is necessary for receptor activation and downstream signalling.
Classification Click here for help
Compound class Antibody
International Nonproprietary Names Click here for help
INN number INN
11557 ordesekimab
Synonyms Click here for help
AMG-714 | AMG714 | MAb146B7 | PRV-015
Database Links Click here for help
GtoPdb PubChem SID 491299828
Search PubMed clinical trials ordesekimab
Search PubMed titles ordesekimab
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