odronextamab   Click here for help

GtoPdb Ligand ID: 12690

Synonyms: Ordspono® | REGN-1979 | REGN1979
Approved drug
odronextamab is an approved drug (EMA (2024))
Compound class: Antibody
Comment: Odronextamab (REGN1979) is a fully human CD3ε/CD20 bispecific IgG4-based antibody that redirects CD3+ cytotoxic T cells to selectively destroy CD20+ve malignant B cells [3]. Fc-mediated effector function has been minimised by modification of the IgG4 Fc domain.
Classification Click here for help
Compound class Antibody
Approved drug? Yes. EMA (2024)
International Nonproprietary Names Click here for help
INN number INN
11035 odronextamab
Synonyms Click here for help
Ordspono® | REGN-1979 | REGN1979
Database Links Click here for help
Specialist databases
IMGT/mAb-DB 962
Other databases
GtoPdb PubChem SID 483123238
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