somatrogon   Click here for help

GtoPdb Ligand ID: 12013

Synonyms: hGH-CTP | MOD-4023 | MOD4023 | Ngenla® | somatrogon-ghla
Approved drug
somatrogon is an approved drug (EMA (2022), FDA (2023))
Compound class: Peptide
Comment: Somatrogon is a recombinant chimeric protein that contains the amino acid sequence of human growth hormone (hGH) and three copies of the 28 aa carboxy-terminal peptide (CTP) from human chorionic gonadotropin (CTP-hGH-CTP-CTP). It acts as a long-acting growth hormone replacement with pharmacokinetics that support once-weekly administration [2].
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Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

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View interactive charts of activity data across species
Classification Click here for help
Compound class Peptide
Approved drug? Yes. EMA (2022)  |  FDA (2023)
International Nonproprietary Names Click here for help
INN number INN
10402 somatrogon
Synonyms Click here for help
hGH-CTP | MOD-4023 | MOD4023 | Ngenla® | somatrogon-ghla
Database Links Click here for help
GtoPdb PubChem SID 464244154
Search PubMed clinical trials somatrogon
Search PubMed titles somatrogon
Search PubMed titles/abstracts somatrogon