epcoritamab   Click here for help

GtoPdb Ligand ID: 11442

Synonyms: epcoritamab-bysp | Epkinly® | GEN-3013 | GEN3013
Approved drug Immunopharmacology Ligand
epcoritamab is an approved drug (FDA (2023))
Compound class: Antibody
Comment: Epcoritamab (GEN3013) is a novel CD3ε/CD20 bispecific IgG1 antibody that redirects CD3+ cytotoxic T cells to selectively destroy CD20+ve malignant B cells [1-2]. Its Fc domain has been mutated to prevent FcγR and complement binding.
Classification Click here for help
Compound class Antibody
Approved drug? Yes (FDA (2023))
International Nonproprietary Names Click here for help
INN number INN
11078 epcoritamab
Synonyms Click here for help
epcoritamab-bysp | Epkinly® | GEN-3013 | GEN3013
Database Links Click here for help
Specialist databases
IMGT/mAb-DB 949
Other databases
GtoPdb PubChem SID 440816811
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