Synonyms: Colobreathe® | polymyxin E | Promixin®
colistin is an approved drug (UK (2006))
Compound class:
Natural product
Comment: Colistin is a cyclic polypeptide (IUPAC condensed sequence Unk-Dab-Thr-Dab-Dab(1)-Dab-D-Leu-Leu-Dab-Dab-Thr-(1)) antibacterial from Bacillus colistinus. It contains Polymyxins E1 and E2 and acts as a detergent on cell membranes.
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Classification ![]() |
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Compound class | Natural product |
Approved drug? | Yes (UK (2006)) |
WHO Essential Medicine | WHO Essential Medicines List (EML) (23rd List, 2023). Access PDF version. Click to view more information about the WHO Model Lists of Essential Medicines. |
International Nonproprietary Names ![]() |
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INN number | INN |
916 | colistin |
Synonyms ![]() |
Colobreathe® | polymyxin E | Promixin® |
Database Links ![]() |
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Specialist databases | |
Antibiotic DB
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Colistin |
Other databases | |
ChEMBL Ligand | CHEMBL499783 |
GtoPdb PubChem SID | 405560235 |
PubChem CID | 5311054 |
Search Google for chemical match using the InChIKey | YKQOSKADJPQZHB-QNPLFGSASA-N |
Search Google for chemicals with the same backbone | YKQOSKADJPQZHB |
Search PubMed clinical trials | colistin |
Search PubMed titles | colistin |
Search PubMed titles/abstracts | colistin |
UniChem Compound Search for chemical match using the InChIKey | YKQOSKADJPQZHB-QNPLFGSASA-N |
UniChem Connectivity Search for chemical match using the InChIKey | YKQOSKADJPQZHB-QNPLFGSASA-N |