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KBP-066   Click here for help

GtoPdb Ligand ID: 10660

Synonyms: DACRA | KBP 066 | KBP066
Compound class: Peptide
Comment: KBP-066 is a Dual Amylin and Calcitonin Receptor Agonist (DACRA), which are a class of peptide, which distinguish themselves from amylin agonists as they activate both the amylin receptor and the calcitonin receptor in a prolonged fashion.
Bioactivity Comments
KBP-066 potently activates the calcitonin and amylin receptors as shown in β-arrestin recruitment assays [1].
Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
CT receptor Hs Agonist Agonist - - - 1
⤷ [1]
Description: β-arrestin recruitment assay
AMY3 receptor Hs Agonist Agonist - - - 1
⤷ [1]
Description: β-arrestin recruitment assay