sonelokimab   Click here for help

GtoPdb Ligand ID: 10491

Synonyms: IL17-MS3086 | IL17MS3086 | SEQ ID 836 [WO2012156219A1]
Immunopharmacology Ligand
Compound class: Antibody
Comment: Sonelokimab (IL17MS3086) is an anti-IL-17A/F single chain camelid nanobody [1]. The peptide sequence for proposed INN sonelokimab is a 100% match for SEQ ID 836 that is claimed in Merck/Ablynx patent WO2012156219A1. IL17MS3086 potently binds to both IL-17A and -F and prevents IL-17R pathway activation (e.g . IL-6 production), and was designed for anti-inflammatory potential. We provide the IL17MS3086 to sonelokimab association in good faith, and await formal disclosure.
Classification Click here for help
Compound class Antibody
International Nonproprietary Names Click here for help
INN number INN
11137 sonelokimab
Synonyms Click here for help
IL17-MS3086 | IL17MS3086 | SEQ ID 836 [WO2012156219A1]
Database Links Click here for help
GtoPdb PubChem SID 385612250
Search PubMed clinical trials sonelokimab
Search PubMed titles sonelokimab
Search PubMed titles/abstracts sonelokimab