sarafotoxin S6c   Click here for help

GtoPdb Ligand ID: 1008

Synonyms: S6C | Sarafotoxin-C | SRTX-C
Compound class: Peptide
Comment: From Atractaspis engaddensis (Israeli burrowing asp). Representations of the chemical structure of sarafotoxin S6c can be found in the links above.
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Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

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View interactive charts of activity data across species
References
1. Kuc RE, Karet FE, Davenport AP. (1995)
Characterization of peptide and nonpeptide antagonists in human kidney.
J Cardiovasc Pharmacol, 26 Suppl 3: S373-5. [PMID:8587419]
2. Russell FD, Davenport AP. (1996)
Characterization of the binding of endothelin ETB selective ligands in human and rat heart.
Br J Pharmacol, 119 (4): 631-6. [PMID:8904635]
3. Williams Jr DL, Jones KL, Pettibone DJ, Lis EV, Clineschmidt BV. (1991)
Sarafotoxin S6c: an agonist which distinguishes between endothelin receptor subtypes.
Biochem Biophys Res Commun, 175 (2): 556-61. [PMID:1850245]