The precursor (PRLH, P81277) for PrRP generates 31 and 20-amino-acid versions. QRFP43 (43RFa) (QRFP, P83859) (named after a pyroglutamylated arginine-phenylalanine-amide peptide) is a 43 amino acid peptide derived from QRFP (P83859) and is also known as P518 or 26RFa. RFRP is an RF amide-related peptide [4] derived from a FMRFamide-related peptide precursor (NPVF, Q9HCQ7), which is cleaved to generate neuropeptide SF (NPFF, O15130), neuropeptide RFRP-1 (NPVF, Q9HCQ7), neuropeptide RFRP-2 (NPVF, Q9HCQ7) and neuropeptide RFRP-3 (NPVF, Q9HCQ7) (neuropeptide NPVF).

The orphan receptor GPR83 (Q9NYM4) shows sequence similarities with NPFF1, NPFF2, PrRP and QRFP receptors.

* Key recommended reading is highlighted with an asterisk

* Samson WK, Taylor MM. (2006) Prolactin releasing peptide (PrRP): an endogenous regulator of cell growth. Peptides, 27 (5): 1099-103. [PMID:16500730]

* Takayanagi Y, Onaka T. (2010) Roles of prolactin-releasing peptide and RFamide related peptides in the control of stress and food intake. FEBS J, 277 (24): 4998-5005. [PMID:21126313]

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