The family of sugar-phosphate exchangers pass particular phosphorylated sugars across intracellular membranes, exchanging for inorganic phosphate. Of the family of sugar phosphate transporters, most information is available on SPX4, the glucose-6-phosphate transporter. This is a 10 TM domain protein with cytoplasmic termini and is associated with the endoplasmic reticulum, with tissue-specific splice variation.

* Key recommended reading is highlighted with an asterisk

Bartoloni L, Antonarakis SE. (2004) The human sugar-phosphate/phosphate exchanger family SLC37. Pflugers Arch, 447 (5): 780-3. [PMID:12811562]

* Chou JY, Mansfield BC. (2014) The SLC37 family of sugar-phosphate/phosphate exchangers. Curr Top Membr, 73: 357-82. [PMID:24745989]

* Chou JY, Sik Jun H, Mansfield BC. (2013) The SLC37 family of phosphate-linked sugar phosphate antiporters. Mol Aspects Med, 34 (2-3): 601-11. [PMID:23506893]

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3. Chen SY, Pan CJ, Nandigama K, Mansfield BC, Ambudkar SV, Chou JY. (2008) The glucose-6-phosphate transporter is a phosphate-linked antiporter deficient in glycogen storage disease type Ib and Ic. FASEB J, 22 (7): 2206-13. [PMID:18337460]

4. Pan CJ, Chen SY, Jun HS, Lin SR, Mansfield BC, Chou JY. (2011) SLC37A1 and SLC37A2 are phosphate-linked, glucose-6-phosphate antiporters. PLoS ONE, 6 (9): e23157. [PMID:21949678]