Top ▲

Glycine recycling

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

Click here for help

« Hide More detailed introduction go icon to follow link

The glycine cleavage system (a.k.a. the glycine decarboxylase complex) is active at mitochondria. It contains four loosely associated proteins that catalyse the following (reversible) reaction: Glycine + tetrahydrofolate + NAD+ <-> 5,10-methylenetetrahydrofolate + CO2 + NH3 + NADH + H+.

Enzymes

Click here for help

glycine cleavage system protein H Show summary » More detailed page go icon to follow link

Comments

Click here for help

Show »

How to cite this family page

Database page citation:

Glycine recycling. Accessed on 11/12/2024. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=1026.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Enzymes. Br J Pharmacol. 180 Suppl 2:S289-373.