ChEMBL ligand: CHEMBL2151321
fms related receptor tyrosine kinase 3 in Human [GtoPdb: 1807] [UniProtKB: P36888] There should be some charts here, you may need to enable JavaScript!
fibroblast growth factor receptor 1 in Human [GtoPdb: 1808] [UniProtKB: P11362] There should be some charts here, you may need to enable JavaScript!
neurotrophic receptor tyrosine kinase 1 in Human [GtoPdb: 1817] [UniProtKB: P04629] There should be some charts here, you may need to enable JavaScript!
ABL proto-oncogene 1, non-receptor tyrosine kinase in Human [GtoPdb: 1923] [UniProtKB: P00519] There should be some charts here, you may need to enable JavaScript!
Bruton tyrosine kinase in Human [GtoPdb: 1948] [UniProtKB: Q06187] There should be some charts here, you may need to enable JavaScript!
FGR proto-oncogene, Src family tyrosine kinase in Human [GtoPdb: 2024] [UniProtKB: P09769] There should be some charts here, you may need to enable JavaScript!
phosphorylase kinase catalytic subunit gamma 2 in Human [GtoPdb: 2147] [UniProtKB: P15735] There should be some charts here, you may need to enable JavaScript!
salt inducible kinase 1 in Human [GtoPdb: 2197] [UniProtKB: P57059] There should be some charts here, you may need to enable JavaScript!
testis specific serine kinase 2 in Human [GtoPdb: 2258] [UniProtKB: Q96PF2] There should be some charts here, you may need to enable JavaScript!
WNK lysine deficient protein kinase 3 in Human [GtoPdb: 2282] [UniProtKB: Q9BYP7] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
fms related receptor tyrosine kinase 3 in Human [GtoPdb: 1807] [UniProtKB: P36888]
GtoPdb	-	-	8.68	pIC50	2.1	nM	IC50	ACS Med Chem Lett (2012) 3: 705-9 [PMID:24900538]
fibroblast growth factor receptor 1 in Human [GtoPdb: 1808] [UniProtKB: P11362]
GtoPdb	-	-	8.06	pIC50	8.7	nM	IC50	ACS Med Chem Lett (2012) 3: 705-9 [PMID:24900538]
neurotrophic receptor tyrosine kinase 1 in Human [GtoPdb: 1817] [UniProtKB: P04629]
GtoPdb	-	-	8.85	pIC50	1.4	nM	IC50	ACS Med Chem Lett (2012) 3: 705-9 [PMID:24900538]
ABL proto-oncogene 1, non-receptor tyrosine kinase in Human [GtoPdb: 1923] [UniProtKB: P00519]
GtoPdb	-	-	8.92	pIC50	1.2	nM	IC50	ACS Med Chem Lett (2012) 3: 705-9 [PMID:24900538]
Bruton tyrosine kinase in Human [GtoPdb: 1948] [UniProtKB: Q06187]
GtoPdb	-	-	8.46	pIC50	3.5	nM	IC50	ACS Med Chem Lett (2012) 3: 705-9 [PMID:24900538]
FGR proto-oncogene, Src family tyrosine kinase in Human [GtoPdb: 2024] [UniProtKB: P09769]
GtoPdb	-	-	8.66	pIC50	2.2	nM	IC50	ACS Med Chem Lett (2012) 3: 705-9 [PMID:24900538]
phosphorylase kinase catalytic subunit gamma 2 in Human [GtoPdb: 2147] [UniProtKB: P15735]
GtoPdb	-	-	8.21	pIC50	6.1	nM	IC50	ACS Med Chem Lett (2012) 3: 705-9 [PMID:24900538]
salt inducible kinase 1 in Human [GtoPdb: 2197] [UniProtKB: P57059]
GtoPdb	-	-	8.26	pIC50	5.5	nM	IC50	ACS Med Chem Lett (2012) 3: 705-9 [PMID:24900538]
testis specific serine kinase 2 in Human [GtoPdb: 2258] [UniProtKB: Q96PF2]
GtoPdb	-	-	7.51	pIC50	30.6	nM	IC50	ACS Med Chem Lett (2012) 3: 705-9 [PMID:24900538]
WNK lysine deficient protein kinase 3 in Human [GtoPdb: 2282] [UniProtKB: Q9BYP7]
GtoPdb	-	-	7	pIC50	99.8	nM	IC50	ACS Med Chem Lett (2012) 3: 705-9 [PMID:24900538]

ChEMBL data shown on this page come from version 35:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]