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The IUPHAR Guide to MALARIA PHARMACOLOGY ligand list

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GtoMPdb (Antimalarial) ligands which are currently, or have been in the past, approved for human clinical use by a regulatory agency.
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A   B   C   D   H   L   M   P   Q   S   T  

Ligand name ID Synonyms
A Back to top
amodiaquine Approved drug PDB Ligand Antimalarial Ligand 10018 Alphaquine®, Amdaquine®, Amoquin®, Camoquin®, Flavoquine®
artemether Approved drug PDB Ligand Antimalarial Ligand 9955 β-artemether, beta-artemether, Coartem® (artemether + lumefantrine)
artenimol Approved drug Antimalarial Ligand 9957 DHA, dihydroartemisinin, GNF-Pf-5634
artesunate Approved drug PDB Ligand Antimalarial Ligand 9956
atovaquone Approved drug PDB Ligand Antimalarial Ligand 9695 566C80, Mepron®, Wellvone®
azithromycin Approved drug PDB Ligand Immunopharmacology Ligand Antimalarial Ligand 6510
 
B Back to top
bortezomib Approved drug PDB Ligand Immunopharmacology Ligand Antimalarial Ligand 6391 peptide boronate, PS-341, Velcade®
 
C Back to top
chloroquine Approved drug PDB Ligand Immunopharmacology Ligand Antimalarial Ligand 5535 Aralen®, chloraquine, Malaquin®
clindamycin Approved drug PDB Ligand Antimalarial Ligand 10607
 
D Back to top
dapsone Approved drug Antimalarial Ligand 10934 Aczone®, NSC-6091
doxycycline Approved drug PDB Ligand Immunopharmacology Ligand Antimalarial Ligand 6464 BMY-28689, Monodox®, Vibramycin®
 
H Back to top
halofantrine Approved drug Antimalarial Ligand 10019 Halfan®, WR-171669
hydroxychloroquine Approved drug Immunopharmacology Ligand Antimalarial Ligand 7198 Dolquine®, Plaquenil®
 
L Back to top
lumefantrine Approved drug Antimalarial Ligand 9969 benflumetol, Coartem® (lumefantrine + artemether)
 
M Back to top
mefloquine Approved drug PDB Ligand Antimalarial Ligand 4252 GNF-Pf-5544, Lariam®, Ro-21-5998-001, WR-142490
mupirocin Approved drug PDB Ligand Antimalarial Ligand 10916 Bactroban®, BRL-4910A, BRL-4910F, Centany®, pseudomonic acid
 
P Back to top
panobinostat Approved drug PDB Ligand Antimalarial Ligand 7489 Farydak®, LBH-589, LBH589
piperaquine Approved drug Antimalarial Ligand 10025
primaquine Approved drug PDB Ligand Antimalarial Ligand 9952
proguanil Approved drug PDB Ligand Antimalarial Ligand 9676 Bigumal®, chloroguanide, Paludrine®
pyrimethamine Approved drug PDB Ligand Antimalarial Ligand 4800 Daraprim®, GNF-Pf-5586, TCMDC-125860
 
Q Back to top
quinidine Approved drug PDB Ligand Antimalarial Ligand 2342 Quinaglute®, Quinidex®, quinidine hydrochloride
quinine Approved drug PDB Ligand Antimalarial Ligand 2510 GNF-Pf-506, Qualaquin®, Quinate®, quinine bisulphate, quinine sulfate
 
S Back to top
sulfadoxine Approved drug Antimalarial Ligand 10173 sulphadoxine
 
T Back to top
tafenoquine Approved drug Antimalarial Ligand 9722 Arakoda®, etaquine, Krintafel®, WR238605