ilginatinib [Ligand Id: 7839] activity data from GtoPdb

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  • Janus kinase 1 in Human [GtoPdb: 2047] [UniProtKB: P23458]
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  • Janus kinase 2 in Human [GtoPdb: 2048] [UniProtKB: O60674]
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  • Janus kinase 3 in Human [GtoPdb: 2049] [UniProtKB: P52333]
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  • tyrosine kinase 2 in Human [GtoPdb: 2269] [UniProtKB: P29597]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Janus kinase 1 in Human [GtoPdb: 2047] [UniProtKB: P23458]
GtoPdb - - 7.48 pIC50 33 nM IC50 Blood Cancer J (2011) 1: e29 [PMID:22829185]
Janus kinase 2 in Human [GtoPdb: 2048] [UniProtKB: O60674]
GtoPdb - - 9.14 pIC50 0.72 nM IC50 Blood Cancer J (2011) 1: e29 [PMID:22829185]
Janus kinase 3 in Human [GtoPdb: 2049] [UniProtKB: P52333]
GtoPdb - - 7.41 pIC50 39 nM IC50 Blood Cancer J (2011) 1: e29 [PMID:22829185]
tyrosine kinase 2 in Human [GtoPdb: 2269] [UniProtKB: P29597]
GtoPdb - - 7.66 pIC50 22 nM IC50 Blood Cancer J (2011) 1: e29 [PMID:22829185]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.