ChEMBL ligand: CHEMBL2349310
A1 receptor/Adenosine A1 receptor in Human [ChEMBL: CHEMBL226] [GtoPdb: 18] [UniProtKB: P30542] There should be some charts here, you may need to enable JavaScript!
C3a receptor/C3a anaphylatoxin chemotactic receptor in Human [ChEMBL: CHEMBL4761] [GtoPdb: 31] [UniProtKB: Q16581] There should be some charts here, you may need to enable JavaScript!
C5a1 receptor/C5a anaphylatoxin chemotactic receptor in Human [ChEMBL: CHEMBL2373] [GtoPdb: 32] [UniProtKB: P21730] There should be some charts here, you may need to enable JavaScript!
C5a2 receptor/C5a anaphylatoxin chemotactic receptor 2 in Human [ChEMBL: CHEMBL4523478] [GtoPdb: 33] [UniProtKB: Q9P296] There should be some charts here, you may need to enable JavaScript!
CX3CR1/C-X3-C chemokine receptor 1 in Human [ChEMBL: CHEMBL4843] [GtoPdb: 74] [UniProtKB: P49238] There should be some charts here, you may need to enable JavaScript!
CXCR2/Interleukin-8 receptor B in Human [ChEMBL: CHEMBL2434] [GtoPdb: 69] [UniProtKB: P25025] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
A1 receptor/Adenosine A1 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL226] [GtoPdb: 18] [UniProtKB: P30542]
ChEMBL	Binding affinity to adenosine A1 receptor (unknown origin)	B	6.88	pKi	132	nM	Ki	J Med Chem (2013) 56: 3177-3190 [PMID:23516963]
C3a receptor/C3a anaphylatoxin chemotactic receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4761] [GtoPdb: 31] [UniProtKB: Q16581]
ChEMBL	GPCR PRESTO-Tango dose-response in antagonist mode with target: C3AR1	F	5	pIC50	>10000	nM	IC50	EUbOPEN Chemogenomics Library - GPCR Dose-Respose
C5a1 receptor/C5a anaphylatoxin chemotactic receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2373] [GtoPdb: 32] [UniProtKB: P21730]
ChEMBL	GPCR PRESTO-Tango dose-response in antagonist mode with target: C5AR1	F	5	pIC50	>10000	nM	IC50	EUbOPEN Chemogenomics Library - GPCR Dose-Respose
C5a2 receptor/C5a anaphylatoxin chemotactic receptor 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4523478] [GtoPdb: 33] [UniProtKB: Q9P296]
ChEMBL	GPCR PRESTO-Tango dose-response in antagonist mode with target: C5AR2	F	6	pIC50	>1000	nM	IC50	EUbOPEN Chemogenomics Library - GPCR Dose-Respose
CX3CR1/C-X3-C chemokine receptor 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4843] [GtoPdb: 74] [UniProtKB: P49238]
GtoPdb	Measuring displacement of [3H]AZD8797/rugocrixan by unlabelled ligand	-	8.14	pKi	7.3	nM	Ki	Biochem J (2016) 473: 641-9 [PMID:26656484]
ChEMBL	Displacement of [125I]-CX3CL1 from human CX3CR1 transfected in HEK293 cells after 24 hrs by scintillation counting analysis	B	8.41	pKi	3.9	nM	Ki	J Med Chem (2013) 56: 3177-3190 [PMID:23516963]
CXCR2/Interleukin-8 receptor B in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2434] [GtoPdb: 69] [UniProtKB: P25025]
ChEMBL	Displacement of [125I]-IL8 from human CXCR2 transfected in HEK293 cells after 4 hrs by microbeta counting analysis	B	5.55	pKi	2800	nM	Ki	J Med Chem (2013) 56: 3177-3190 [PMID:23516963]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]