4-hydroxybenzaldehyde [Ligand Id: 13597] activity data from GtoPdb and ChEMBL
Click here for a description of the charts and data table
Please tell us if you are using this feature and what you think!
| ChEMBL ligand: CHEMBL14193 (Para-Hydroxybenzaldehyde, p-hydroxybenzaldehyde) |
|---|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
|
There should be some charts here, you may need to enable JavaScript!
|
| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| 4-aminobutyrate aminotransferase/Gamma-amino-N-butyrate transaminase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2044] [GtoPdb: 2464] [UniProtKB: P80404] | ||||||||
| ChEMBL | Inhibitory activity against GABAT | B | 4.78 | pIC50 | 16500 | nM | IC50 | Bioorg Med Chem Lett (2006) 16: 592-595 [PMID:16290145] |
| 4-aminobutyrate aminotransferase/Gamma-amino-N-butyrate transaminase in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3148] [GtoPdb: 2464] [UniProtKB: P50554] | ||||||||
| ChEMBL | Inhibition of GABA transaminase in rat brain by Kitz-Wilson plot | B | 4.78 | pIC50 | 16500 | nM | IC50 | Bioorg Med Chem Lett (2009) 19: 731-734 [PMID:19138517] |
| CoV Replicase polyprotein 1ab/CoV RNA-dependent RNA polymerase/CoV Non-structural protein 15/CoV Non-structural protein 13/Replicase polyprotein 1ab in Severe acute respiratory syndrome coronavirus 2 (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4523582] [GtoPdb: 3125, 3139, 3206, 3261] [UniProtKB: P0DTD1] | ||||||||
| ChEMBL | Inhibition of SARS-CoV-2 papain-like protease using ISG15-Rh as substrate | B | 5.4 | pIC50 | 3990 | nM | IC50 | J Med Chem (2022) 65: 7561-7580 [PMID:35620927] |
| aldehyde dehydrogenase 5 family member A1/Succinate semialdehyde dehydrogenase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1911] [GtoPdb: 2466] [UniProtKB: P51649] | ||||||||
| ChEMBL | Inhibitory activity against SSADH | B | 4.61 | pIC50 | 24700 | nM | IC50 | Bioorg Med Chem Lett (2006) 16: 592-595 [PMID:16290145] |
| CoV Papain-like protease in SARS-CoV-2 [GtoPdb: 3132] [UniProtKB: P0DTC1] | ||||||||
| GtoPdb | - | - | 5.4 | pIC50 | 3990 | nM | IC50 | J Med Chem (2022) 65: 7561-7580 [PMID:35620927] |
ChEMBL data shown on this page come from version 34:
Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
