compound 36 [PMID: 21958547] [Ligand Id: 9391] activity data from GtoPdb

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  • Bruton tyrosine kinase in Human [GtoPdb: 1948] [UniProtKB: Q06187]
Created with Highcharts 10.3.3ValuesChart context menuBruton tyrosine kinasepKd HumanpKi HumanpIC50 HumanpEC50 Human0246810Highcharts.com
  • LCK proto-oncogene, Src family tyrosine kinase in Human [GtoPdb: 2053] [UniProtKB: P06239]
Created with Highcharts 10.3.3ValuesChart context menuLCK proto-oncogene, Src family tyrosine kinasepKd HumanpKi HumanpIC50 HumanpEC50 Human01234567Highcharts.com
  • LYN proto-oncogene, Src family tyrosine kinase in Human [GtoPdb: 2060] [UniProtKB: P07948]
Created with Highcharts 10.3.3ValuesChart context menuLYN proto-oncogene, Src family tyrosine kinasepKd HumanpKi HumanpIC50 HumanpEC50 Human01234567Highcharts.com
  • SRC proto-oncogene, non-receptor tyrosine kinase in Human [GtoPdb: 2206] [UniProtKB: P12931]
Created with Highcharts 10.3.3ValuesChart context menuSRC proto-oncogene, non-receptor tyrosine kinasepKd HumanpKi HumanpIC50 HumanpEC50 Human02468Highcharts.com
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Bruton tyrosine kinase in Human [GtoPdb: 1948] [UniProtKB: Q06187]
GtoPdb - - 8.71 pIC50 1.93 nM IC50 Bioorg Med Chem Lett (2011) 21: 6258-63 [PMID:21958547]
LCK proto-oncogene, Src family tyrosine kinase in Human [GtoPdb: 2053] [UniProtKB: P06239]
GtoPdb - - 6.11 pIC50 772 nM IC50 Bioorg Med Chem Lett (2011) 21: 6258-63 [PMID:21958547]
LYN proto-oncogene, Src family tyrosine kinase in Human [GtoPdb: 2060] [UniProtKB: P07948]
GtoPdb - - 6.2 pIC50 624 nM IC50 Bioorg Med Chem Lett (2011) 21: 6258-63 [PMID:21958547]
SRC proto-oncogene, non-receptor tyrosine kinase in Human [GtoPdb: 2206] [UniProtKB: P12931]
GtoPdb - - 6.53 pIC50 298 nM IC50 Bioorg Med Chem Lett (2011) 21: 6258-63 [PMID:21958547]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.