eCF506 [Ligand Id: 9186] activity data from GtoPdb

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  • ABL proto-oncogene 1, non-receptor tyrosine kinase in Human [GtoPdb: 1923] [UniProtKB: P00519]
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  • BLK proto-oncogene, Src family tyrosine kinase in Human [GtoPdb: 1940] [UniProtKB: P51451]
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  • FGR proto-oncogene, Src family tyrosine kinase in Human [GtoPdb: 2024] [UniProtKB: P09769]
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  • fyn related Src family tyrosine kinase in Human [GtoPdb: 2025] [UniProtKB: P42685]
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  • FYN proto-oncogene, Src family tyrosine kinase in Human [GtoPdb: 2026] [UniProtKB: P06241]
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  • HCK proto-oncogene, Src family tyrosine kinase in Human [GtoPdb: 2032] [UniProtKB: P08631]
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  • LCK proto-oncogene, Src family tyrosine kinase in Human [GtoPdb: 2053] [UniProtKB: P06239]
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  • LYN proto-oncogene, Src family tyrosine kinase in Human [GtoPdb: 2060] [UniProtKB: P07948]
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  • SRC proto-oncogene, non-receptor tyrosine kinase in Human [GtoPdb: 2206] [UniProtKB: P12931]
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  • YES proto-oncogene 1, Src family tyrosine kinase in Human [GtoPdb: 2284] [UniProtKB: P07947]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
ABL proto-oncogene 1, non-receptor tyrosine kinase in Human [GtoPdb: 1923] [UniProtKB: P00519]
GtoPdb - - 6.32 pIC50 479 nM IC50 J Med Chem (2016) 59: 4697-710 [PMID:27115835]
BLK proto-oncogene, Src family tyrosine kinase in Human [GtoPdb: 1940] [UniProtKB: P51451]
GtoPdb - - 8.27 pIC50 5.4 nM IC50 J Med Chem (2016) 59: 4697-710 [PMID:27115835]
FGR proto-oncogene, Src family tyrosine kinase in Human [GtoPdb: 2024] [UniProtKB: P09769]
GtoPdb - - 9.3 pIC50 <0.5 nM IC50 J Med Chem (2016) 59: 4697-710 [PMID:27115835]
fyn related Src family tyrosine kinase in Human [GtoPdb: 2025] [UniProtKB: P42685]
GtoPdb - - 8.55 pIC50 2.8 nM IC50 J Med Chem (2016) 59: 4697-710 [PMID:27115835]
FYN proto-oncogene, Src family tyrosine kinase in Human [GtoPdb: 2026] [UniProtKB: P06241]
GtoPdb - - 8.68 pIC50 2.1 nM IC50 J Med Chem (2016) 59: 4697-710 [PMID:27115835]
HCK proto-oncogene, Src family tyrosine kinase in Human [GtoPdb: 2032] [UniProtKB: P08631]
GtoPdb - - 8.55 pIC50 2.8 nM IC50 J Med Chem (2016) 59: 4697-710 [PMID:27115835]
LCK proto-oncogene, Src family tyrosine kinase in Human [GtoPdb: 2053] [UniProtKB: P06239]
GtoPdb - - 9.3 pIC50 <0.5 nM IC50 J Med Chem (2016) 59: 4697-710 [PMID:27115835]
LYN proto-oncogene, Src family tyrosine kinase in Human [GtoPdb: 2060] [UniProtKB: P07948]
GtoPdb - - 9.1 pIC50 0.8 nM IC50 J Med Chem (2016) 59: 4697-710 [PMID:27115835]
SRC proto-oncogene, non-receptor tyrosine kinase in Human [GtoPdb: 2206] [UniProtKB: P12931]
GtoPdb - - 9.3 pIC50 <0.5 nM IC50 J Med Chem (2016) 59: 4697-710 [PMID:27115835]
YES proto-oncogene 1, Src family tyrosine kinase in Human [GtoPdb: 2284] [UniProtKB: P07947]
GtoPdb - - 9.3 pIC50 <0.5 nM IC50 J Med Chem (2016) 59: 4697-710 [PMID:27115835]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.