lumateperone [Ligand Id: 9099] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL3545045 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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| 5-HT2A receptor in Human [GtoPdb: 6] [UniProtKB: P28223] | ||||||||
| GtoPdb | - | - | 9.3 | pKi | 0.5 | nM | Ki |
Psychopharmacology (Berl.) (2015) 232: 605-21 [PMID:25120104]; J Med Chem (2014) 57: 2670-82 [PMID:24559051] |
| D2 receptor in Human [GtoPdb: 215] [UniProtKB: P14416] | ||||||||
| GtoPdb | - | - | 7.49 | pKi | 32 | nM | Ki |
Psychopharmacology (Berl.) (2015) 232: 605-21 [PMID:25120104]; J Med Chem (2014) 57: 2670-82 [PMID:24559051] |
| SERT in Human [GtoPdb: 928] [UniProtKB: P31645] | ||||||||
| GtoPdb | - | - | 7.21 | pKi | 62 | nM | Ki |
Psychopharmacology (Berl.) (2015) 232: 605-21 [PMID:25120104]; J Med Chem (2014) 57: 2670-82 [PMID:24559051] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
