LY2874455 [Ligand Id: 8104] activity data from GtoPdb

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  • fibroblast growth factor receptor 1 in Human [GtoPdb: 1808] [UniProtKB: P11362]
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  • fibroblast growth factor receptor 2 in Human [GtoPdb: 1809] [UniProtKB: P21802]
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  • fibroblast growth factor receptor 3 in Human [GtoPdb: 1810] [UniProtKB: P22607]
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  • fibroblast growth factor receptor 4 in Human [GtoPdb: 1811] [UniProtKB: P22455]
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  • kinase insert domain receptor in Human [GtoPdb: 1813] [UniProtKB: P35968]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
fibroblast growth factor receptor 1 in Human [GtoPdb: 1808] [UniProtKB: P11362]
GtoPdb - - 8.55 pIC50 2.8 nM IC50 Mol Cancer Ther (2011) 10: 2200-10 [PMID:21900693]
fibroblast growth factor receptor 2 in Human [GtoPdb: 1809] [UniProtKB: P21802]
GtoPdb - - 8.59 pIC50 2.6 nM IC50 Mol Cancer Ther (2011) 10: 2200-10 [PMID:21900693]
fibroblast growth factor receptor 3 in Human [GtoPdb: 1810] [UniProtKB: P22607]
GtoPdb - - 8.19 pIC50 6.4 nM IC50 Mol Cancer Ther (2011) 10: 2200-10 [PMID:21900693]
fibroblast growth factor receptor 4 in Human [GtoPdb: 1811] [UniProtKB: P22455]
GtoPdb - - 8.22 pIC50 6 nM IC50 Mol Cancer Ther (2011) 10: 2200-10 [PMID:21900693]
kinase insert domain receptor in Human [GtoPdb: 1813] [UniProtKB: P35968]
GtoPdb In vitro biochemical assay result - 8.15 pIC50 7 nM IC50 Mol Cancer Ther (2011) 10: 2200-10 [PMID:21900693]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.