XD14 [Ligand Id: 7524] activity data from GtoPdb

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  • bromodomain containing 2 in Human [GtoPdb: 1944] [UniProtKB: P25440]
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  • bromodomain containing 4 in Human [GtoPdb: 1945] [UniProtKB: O60885]
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  • bromodomain containing 3 in Human [GtoPdb: 2725] [UniProtKB: Q15059]
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  • bromodomain testis associated in Human [GtoPdb: 2729] [UniProtKB: Q58F21]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
bromodomain containing 2 in Human [GtoPdb: 1944] [UniProtKB: P25440]
GtoPdb Assay using recombinant BRD2-BD1. - 6.77 pKd 170 nM Kd Angew Chem Int Ed Engl (2013) 52: 14055-9 [PMID:24272870]
bromodomain containing 4 in Human [GtoPdb: 1945] [UniProtKB: O60885]
GtoPdb Assay using recombinant BRD4-BD1. - 6.8 pKd 160 nM Kd Angew Chem Int Ed Engl (2013) 52: 14055-9 [PMID:24272870]
bromodomain containing 3 in Human [GtoPdb: 2725] [UniProtKB: Q15059]
GtoPdb Assay using recombinant BRD3-BD1. - 6.42 pKd 380 nM Kd Angew Chem Int Ed Engl (2013) 52: 14055-9 [PMID:24272870]
bromodomain testis associated in Human [GtoPdb: 2729] [UniProtKB: Q58F21]
GtoPdb Assay using recombinant BRDT-BD1. - 5.92 pKd 1200 nM Kd Angew Chem Int Ed Engl (2013) 52: 14055-9 [PMID:24272870]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.