ChEMBL ligand: CHEMBL2393130 (Apabetalone, RVX000222, RVX-000222, RVX-208)
bromodomain containing 2/Bromodomain-containing protein 2 in Human [ChEMBL: CHEMBL1293289] [GtoPdb: 1944] [UniProtKB: P25440] There should be some charts here, you may need to enable JavaScript!
bromodomain containing 3/Bromodomain-containing protein 3 in Human [ChEMBL: CHEMBL1795186] [GtoPdb: 2725] [UniProtKB: Q15059] There should be some charts here, you may need to enable JavaScript!
bromodomain containing 4/Bromodomain-containing protein 4 in Human [ChEMBL: CHEMBL1163125] [GtoPdb: 1945] [UniProtKB: O60885] There should be some charts here, you may need to enable JavaScript!
bromodomain testis associated/Bromodomain testis-specific protein in Human [ChEMBL: CHEMBL1795185] [GtoPdb: 2729] [UniProtKB: Q58F21] There should be some charts here, you may need to enable JavaScript!
CREB binding protein/CREB-binding protein in Human [ChEMBL: CHEMBL5747] [GtoPdb: 2734] [UniProtKB: Q92793] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
bromodomain containing 2/Bromodomain-containing protein 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1293289] [GtoPdb: 1944] [UniProtKB: P25440]
ChEMBL	Binding affinity to human BRD2 bromodomain 1 by isothermal titration calorimetry	B	4.77	pKd	16900	nM	Kd	J Med Chem (2016) 59: 1492-1500 [PMID:26367539]
ChEMBL	Inhibition of human 6x-His-tagged BRD2 bromodomain 1 expressed in Escherichia coli	B	5.24	pKd	5800	nM	Kd	J Med Chem (2018) 61: 9316-9334 [PMID:30253095]
ChEMBL	Binding affinity to human BRD2 bromodomain 1 expressed in Escherichia coli BL21 (DE3) cells by isothermal titration calorimetry	B	5.24	pKd	5800	nM	Kd	J Med Chem (2016) 59: 1492-1500 [PMID:26367539]
ChEMBL	Binding affinity to recombinant BRD2 BD1 (unknown origin) incubated for 1 hr by TR-FRET assay	B	5.24	pKd	5780	nM	Kd	J Med Chem (2020) 63: 5242-5256 [PMID:32255647]
ChEMBL	Inhibition of recombinant human His6-tagged BRD2 bromodomain 1 expressed in Escherichia coli BL21(DE3)-R3-pRARE2 cells	B	5.24	pKd	5780	nM	Kd	J Med Chem (2017) 60: 4533-4558 [PMID:28195723]
ChEMBL	Binding affinity to recombinant BRD2 BD2 (unknown origin) incubated for 1 hr by TR-FRET assay	B	6.6	pKd	251	nM	Kd	J Med Chem (2020) 63: 5242-5256 [PMID:32255647]
ChEMBL	Inhibition of recombinant human His6-tagged BRD2 bromodomain 2 expressed in Escherichia coli BL21(DE3)-R3-pRARE2 cells	B	6.6	pKd	251	nM	Kd	J Med Chem (2017) 60: 4533-4558 [PMID:28195723]
ChEMBL	Inhibition of human 6x-His-tagged BRD2 bromodomain 2 expressed in Escherichia coli	B	6.6	pKd	250	nM	Kd	J Med Chem (2018) 61: 9316-9334 [PMID:30253095]
ChEMBL	Binding affinity to human BRD2 bromodomain 2 expressed in Escherichia coli BL21 (DE3) cells by isothermal titration calorimetry	B	6.6	pKd	250	nM	Kd	J Med Chem (2016) 59: 1492-1500 [PMID:26367539]
ChEMBL	Binding affinity to human BRD2 bromodomain 2 by isothermal titration calorimetry	B	6.69	pKd	206	nM	Kd	J Med Chem (2016) 59: 1492-1500 [PMID:26367539]
ChEMBL	Inhibition of BRD2 BD1 (unknown origin) after 1 hr by TR-FRET assay	B	5.24	pIC50	5780	nM	IC50	Eur J Med Chem (2018) 151: 450-461 [PMID:29649741]
ChEMBL	Binding affinity BRD2 BD1 (unknown origin) incubated for 1 hr by TR-FRET assay	B	5.24	pIC50	5697	nM	IC50	J Med Chem (2022) 65: 2388-2408 [PMID:34982556]
ChEMBL	Inhibition of BRD2 BD2 (unknown origin) after 1 hr by TR-FRET assay	B	6.6	pIC50	251	nM	IC50	Eur J Med Chem (2018) 151: 450-461 [PMID:29649741]
ChEMBL	Binding affinity BRD2 BD2 (unknown origin) incubated for 1 hr by TR-FRET assay	B	6.61	pIC50	246	nM	IC50	J Med Chem (2022) 65: 2388-2408 [PMID:34982556]
GtoPdb	Measured using a TR-FRET assay to evaluate binding to BD2 of BRD2.	-	7.05	pIC50	90	nM	IC50	PLoS ONE (2013) 8: e83190 [PMID:24391744]
bromodomain containing 3/Bromodomain-containing protein 3 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1795186] [GtoPdb: 2725] [UniProtKB: Q15059]
ChEMBL	Inhibition of recombinant human His6-tagged BRD3 bromodomain 1 expressed in Escherichia coli BL21(DE3)-R3-pRARE2 cells	B	5.39	pKd	4065	nM	Kd	J Med Chem (2017) 60: 4533-4558 [PMID:28195723]
ChEMBL	Binding affinity to human BRD3 BD2 by ITC method	B	5.4	pKd	4000	nM	Kd	J Med Chem (2018) 61: 4317-4334 [PMID:29656650]
ChEMBL	Inhibition of human 6x-His-tagged BRD3 bromodomain 1 expressed in Escherichia coli	B	5.4	pKd	4000	nM	Kd	J Med Chem (2018) 61: 9316-9334 [PMID:30253095]
ChEMBL	Binding affinity to recombinant BRD3 BD1 (unknown origin) incubated for 1 hr by TR-FRET assay	B	5.4	pKd	3962	nM	Kd	J Med Chem (2020) 63: 5242-5256 [PMID:32255647]
ChEMBL	Binding affinity to recombinant BRD3 BD2 (unknown origin) incubated for 1 hr by TR-FRET assay	B	6.69	pKd	203	nM	Kd	J Med Chem (2020) 63: 5242-5256 [PMID:32255647]
ChEMBL	Inhibition of recombinant human His6-tagged BRD3 bromodomain 2 expressed in Escherichia coli BL21(DE3)-R3-pRARE2 cells	B	6.71	pKd	195	nM	Kd	J Med Chem (2017) 60: 4533-4558 [PMID:28195723]
ChEMBL	Inhibition of human 6x-His-tagged BRD3 bromodomain 2 expressed in Escherichia coli	B	6.72	pKd	190	nM	Kd	J Med Chem (2018) 61: 9316-9334 [PMID:30253095]
GtoPdb	AlphaScreen data for bromodomain 1 of BRD3.	-	4.06	pIC50	87000	nM	IC50	Proc Natl Acad Sci USA (2013) 110: 19754-9 [PMID:24248379]
ChEMBL	Displacement of tetra-acetylated histone H4 peptide from recombinant human His-tagged BRD3 BD1 expressed in bacterial expression system by alphascreen assay	B	4.06	pIC50	87000	nM	IC50	J Med Chem (2019) 62: 11080-11107 [PMID:31789032]
GtoPdb	AlphaScreen data assessing the bromodomain 2 domain of BRD3.	-	5.31	pIC50	4900	nM	IC50	Proc Natl Acad Sci USA (2013) 110: 19754-9 [PMID:24248379]
ChEMBL	Inhibition of BRD3 BD1 (unknown origin) after 1 hr by TR-FRET assay	B	5.4	pIC50	3962	nM	IC50	Eur J Med Chem (2018) 151: 450-461 [PMID:29649741]
ChEMBL	Binding affinity BRD3 BD1 (unknown origin) incubated for 1 hr by TR-FRET assay	B	5.41	pIC50	3878	nM	IC50	J Med Chem (2022) 65: 2388-2408 [PMID:34982556]
ChEMBL	Displacement of tetra-acetylated histone H4 peptide from recombinant human His-tagged BRD3 BD2 expressed in bacterial expression system by alphascreen assay	B	6.29	pIC50	510	nM	IC50	J Med Chem (2019) 62: 11080-11107 [PMID:31789032]
ChEMBL	Inhibition of human His-tagged BRD3 bromodomain 2 using biotin-H4K5acK8acK12acK16ac as substrate incubated for 30 mins by alphascreen assay	B	6.29	pIC50	510	nM	IC50	J Med Chem (2016) 59: 1565-1579 [PMID:26731490]
GtoPdb	Measured using a TR-FRET assay to evaluate binding to BD2 of BRD3.	-	6.55	pIC50	280	nM	IC50	PLoS ONE (2013) 8: e83190 [PMID:24391744]
ChEMBL	Binding affinity BRD3 BD2 (unknown origin) incubated for 1 hr by TR-FRET assay	B	6.66	pIC50	217	nM	IC50	J Med Chem (2022) 65: 2388-2408 [PMID:34982556]
ChEMBL	Inhibition of BRD3 BD2 (unknown origin) after 1 hr by TR-FRET assay	B	6.69	pIC50	203	nM	IC50	Eur J Med Chem (2018) 151: 450-461 [PMID:29649741]
bromodomain containing 4/Bromodomain-containing protein 4 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1163125] [GtoPdb: 1945] [UniProtKB: O60885]
ChEMBL	Binding affinity to human BRD4 bromodomain 1 by isothermal titration calorimetry	B	5.05	pKd	8930	nM	Kd	J Med Chem (2016) 59: 1492-1500 [PMID:26367539]
ChEMBL	Inhibition of BRD4-BD1 (unknown origin) assessed as dissociation constant by ITC method	B	5.39	pKd	4100	nM	Kd	J Med Chem (2022) 65: 5660-5674 [PMID:35348328]
ChEMBL	Binding affinity to recombinant BRD4 BD1 (unknown origin) incubated for 1 hr by TR-FRET assay	B	5.94	pKd	1142	nM	Kd	J Med Chem (2020) 63: 5242-5256 [PMID:32255647]
ChEMBL	Inhibition of recombinant human His6-tagged BRD4 bromodomain 1 expressed in Escherichia coli BL21(DE3)-R3-pRARE2 cells preincubated for 30 mins followed by H4K5acK8acK12acK16ac peptide substrate addition after 30 mins by alphascreen assay	B	5.94	pKd	1142	nM	Kd	J Med Chem (2017) 60: 4533-4558 [PMID:28195723]
ChEMBL	Binding affinity to human BRD4 BD1 by isothermal calorimetry analysis	B	5.94	pKd	1142	nM	Kd	J Med Chem (2020) 63: 5585-5623 [PMID:32324999]
ChEMBL	Binding affinity to BRD4 bromodomain 1 (unknown origin) by isothermal titration calorimetric analysis	B	5.96	pKd	1100	nM	Kd	J Med Chem (2016) 59: 1271-1298 [PMID:26572217]
ChEMBL	Binding affinity to human BRD4 bromodomain 1 expressed in Escherichia coli BL21 (DE3) cells by isothermal titration calorimetry	B	5.96	pKd	1100	nM	Kd	J Med Chem (2016) 59: 1492-1500 [PMID:26367539]
ChEMBL	Inhibition of human 6x-His-tagged BRD4 bromodomain 1 expressed in Escherichia coli	B	5.96	pKd	1100	nM	Kd	J Med Chem (2018) 61: 9316-9334 [PMID:30253095]
ChEMBL	Binding affinity to human BRD4 bromodomain 2 by isothermal titration calorimetry	B	6.52	pKd	303	nM	Kd	J Med Chem (2016) 59: 1492-1500 [PMID:26367539]
ChEMBL	Inhibition of BRD4-BD2 (unknown origin) assessed as dissociation constant by ITC method	B	6.7	pKd	200	nM	Kd	J Med Chem (2022) 65: 5660-5674 [PMID:35348328]
ChEMBL	Binding affinity to human BRD4 bromodomain 2 expressed in Escherichia coli BL21 (DE3) cells by isothermal titration calorimetry	B	6.85	pKd	140	nM	Kd	J Med Chem (2016) 59: 1492-1500 [PMID:26367539]
ChEMBL	Binding affinity to BRD4 bromodomain 2 (unknown origin) by isothermal titration calorimetric analysis	B	6.85	pKd	140	nM	Kd	J Med Chem (2016) 59: 1271-1298 [PMID:26572217]
ChEMBL	Inhibition of recombinant human His6-tagged BRD4 bromodomain 2 expressed in Escherichia coli BL21(DE3)-R3-pRARE2 cells preincubated for 30 mins followed by HSGRGK(Ac)GGK(Ac)GLGK(Ac)GGAK(Ac)RHRK(Biotin)-OH peptide substrate addition after 30 mins by alphascreen assay	B	6.87	pKd	135	nM	Kd	J Med Chem (2017) 60: 4533-4558 [PMID:28195723]
ChEMBL	Binding affinity to N-terminal His-tagged BRD4 BD2 (unknown origin) by isothermal calorimetric titration assay	B	6.87	pKd	135	nM	Kd	J Med Chem (2020) 63: 9070-9092 [PMID:32691591]
ChEMBL	Binding affinity to recombinant BRD4 BD2 (unknown origin) incubated for 1 hr by TR-FRET assay	B	6.87	pKd	135	nM	Kd	J Med Chem (2020) 63: 5242-5256 [PMID:32255647]
ChEMBL	Binding affinity to human BRD4 BD2 by isothermal calorimetry analysis	B	6.87	pKd	135	nM	Kd	J Med Chem (2020) 63: 5585-5623 [PMID:32324999]
ChEMBL	Inhibition of human 6x-His-tagged BRD4 bromodomain 2 expressed in Escherichia coli	B	6.89	pKd	130	nM	Kd	J Med Chem (2018) 61: 9316-9334 [PMID:30253095]
ChEMBL	Inhibition of human His-tagged BRD4 BD1 (49 to 170 residues) using H-SGRGK(Ac)GGK(Ac)GLGK-(Ac)GGAK(Ac)RHRK(Biotin)-OH as substrate preincubated for 30 mins followed by substrate addition measured after 30 mins by TR-FRET assay	B	5	pIC50	>10000	nM	IC50	Eur J Med Chem (2016) 121: 294-299 [PMID:27266999]
ChEMBL	Inhibition of His/thioredoxin-tagged human recombinant BRD4 bromodomain-1 (43 to 166 residues) expressed in Escherichia coli BL21 Star (DE3) pre-incubated for 30 mins followed by biotinylated histone peptide H4 addition measured after 30 mins by AlphaScreen assay	B	5	pIC50	>10000	nM	IC50	J Med Chem (2017) 60: 9990-10012 [PMID:29172540]
ChEMBL	Displacement of (+)-JQ1 from 6H-Thr BRD4 Y390A mutant BD1 (unknown origin) after 30 mins by TR-FRET assay	B	5.2	pIC50	6309.57	nM	IC50	J Med Chem (2018) 61: 4317-4334 [PMID:29656650]
ChEMBL	Inhibition of BRD4 in human SAE cells assessed as reduction in TLR3 agonist poly(I:C) -induced IL-8 RNA expression preincubated for 24 hrs followed by poly(I:C) addition and measured after 4 hrs by SYBR green dye-based qRT-PCR analysis	B	5.41	pIC50	3850	nM	IC50	Eur J Med Chem (2018) 151: 450-461 [PMID:29649741]
ChEMBL	Inhibition of BRD4 in human SAE cells assessed as reduction in TLR3 agonist poly(I:C) -induced grobeta RNA expression preincubated for 24 hrs followed by poly(I:C) addition and measured after 4 hrs by SYBR green dye-based qRT-PCR analysis	B	5.43	pIC50	3730	nM	IC50	Eur J Med Chem (2018) 151: 450-461 [PMID:29649741]
ChEMBL	Inhibition of BRD4 in poly(I:C)-stimulated human SAECs TLR3-inducible IL-6 gene expression pre-incubated for 24 hrs before poly(I:C) stimulation for 4 hrs by qRT-PCR analysis	B	5.48	pIC50	3290	nM	IC50	J Med Chem (2020) 63: 5242-5256 [PMID:32255647]
ChEMBL	Inhibition of biotinylated H4 K5,8,12,16Ac peptide binding to GST-tagged BRD4 bromodomain1 (unknown origin) measured after 60 mins by AlphaScreen assay	B	5.51	pIC50	3100	nM	IC50	Bioorg Med Chem (2019) 27: 1871-1881 [PMID:30926312]
ChEMBL	Inhibition of BRD4 in human SAE cells assessed as reduction in TLR3 agonist poly(I:C) -induced ISG56 RNA expression preincubated for 24 hrs followed by poly(I:C) addition and measured after 4 hrs by SYBR green dye-based qRT-PCR analysis	B	5.56	pIC50	2740	nM	IC50	Eur J Med Chem (2018) 151: 450-461 [PMID:29649741]
ChEMBL	Inhibition of BRD4 in human SAE cells assessed as reduction in TLR3 agonist poly(I:C) -induced ISG54 RNA expression preincubated for 24 hrs followed by poly(I:C) addition and measured after 4 hrs by SYBR green dye-based qRT-PCR analysis	B	5.58	pIC50	2630	nM	IC50	Eur J Med Chem (2018) 151: 450-461 [PMID:29649741]
ChEMBL	Inhibition of GST-tagged BRD4 bromodomain (unknown origin) using biotinylated histone H4KAc peptide (1 to 21 residues) as substrate by HTRF assay	B	5.61	pIC50	2450	nM	IC50	J Med Chem (2020) 63: 3678-3700 [PMID:32153186]
ChEMBL	Inhibition of human BRD4 bromo domain 1	B	5.7	pIC50	1985	nM	IC50	Bioorg Med Chem Lett (2017) 27: 4051-4055 [PMID:28765013]
ChEMBL	Displacement of tetra-acetylated histone H4 peptide from recombinant human N-terminal His-tagged BRD4 BD1 incubated for 2 hrs by TR-FRET assay	B	5.74	pIC50	1800	nM	IC50	J Med Chem (2019) 62: 11080-11107 [PMID:31789032]
ChEMBL	Inhibition of BRD4 in poly(I:C)-stimulated human SAECs TLR3-inducible CIG5 gene expression pre-incubated for 24 hrs before poly(I:C) stimulation for 4 hrs by qRT-PCR analysis	B	5.78	pIC50	1660	nM	IC50	J Med Chem (2020) 63: 5242-5256 [PMID:32255647]
ChEMBL	Displacement of (+)-JQ1 from 6H-Thr BRD4 Y97A mutant BD2 (unknown origin) after 30 mins by TR-FRET assay	B	5.8	pIC50	1584.89	nM	IC50	J Med Chem (2018) 61: 4317-4334 [PMID:29656650]
ChEMBL	Binding affinity recombinant human BRD4 BD1 (42 to 168 residues) expressed in Escherichia coli BL21(DE3) incubated for 1 hr by TR-FRET assay	B	5.94	pIC50	1151	nM	IC50	J Med Chem (2022) 65: 2388-2408 [PMID:34982556]
ChEMBL	Inhibition of BRD4 BD1 (unknown origin) after 1 hr by TR-FRET assay	B	5.94	pIC50	1142	nM	IC50	Eur J Med Chem (2018) 151: 450-461 [PMID:29649741]
ChEMBL	Inhibition of BRD4 bromodomain-1 (unknown origin) by europium based LANCE TR-FRET assay	B	6.19	pIC50	645	nM	IC50	Bioorg Med Chem (2015) 23: 953-959 [PMID:25678016]
ChEMBL	Inhibition of human BRD4 BD2 (342 to 460 residues) at 30 uM preincubated for 30 mins followed by substrate addition measured after 30 mins by TR-FRET assay	B	6.21	pIC50	610	nM	IC50	Eur J Med Chem (2016) 121: 294-299 [PMID:27266999]
ChEMBL	Inhibition of recombinant full length human N-terminal His6-tagged BRD4 (2 to 1362 residues) expressed in baculovirus infected insect cells using histone H4 peptide as substrate by alpha screen assay	B	6.29	pIC50	510	nM	IC50	Eur J Med Chem (2019) 163: 281-294 [PMID:30529546]
ChEMBL	Inhibition of human recombinant N-terminal 6his-tagged BRD4 bromodomain 2 expressed in Escherichia coli BL21(DE3) using using H4 peptide as substrate by alphascreen assay	B	6.29	pIC50	510	nM	IC50	Bioorg Med Chem Lett (2019) 29: 126577-126577 [PMID:31421967]
ChEMBL	Inhibition of human BRD4 bromodomain2 by Alphascreen assay	B	6.29	pIC50	510	nM	IC50	Bioorg Med Chem Lett (2017) 27: 4051-4055 [PMID:28765013]
ChEMBL	Inhibition of BRD4 BD2 (unknown origin) after 1 hr by TR-FRET assay	B	6.87	pIC50	135	nM	IC50	Eur J Med Chem (2018) 151: 450-461 [PMID:29649741]
ChEMBL	Binding affinity human BRD4 BD2 incubated for 1 hr by TR-FRET assay	B	6.88	pIC50	132	nM	IC50	J Med Chem (2022) 65: 2388-2408 [PMID:34982556]
ChEMBL	Inhibition of biotinylated H4 K5,8,12,16Ac peptide binding to GST-tagged BRD4 bromodomain2 (unknown origin) measured after 60 mins by AlphaScreen assay	B	7	pIC50	100	nM	IC50	Bioorg Med Chem (2019) 27: 1871-1881 [PMID:30926312]
ChEMBL	Inhibition of human BRD4 bromo domain 2	B	7.17	pIC50	67	nM	IC50	Bioorg Med Chem Lett (2017) 27: 4051-4055 [PMID:28765013]
ChEMBL	Inhibition of BRD4 bromodomain 2 (unknown origin) incubated for 30 mins by ELISA	B	7.36	pIC50	43.8	nM	IC50	Bioorg Med Chem Lett (2019) 29: 2168-2172 [PMID:31257080]
ChEMBL	Displacement of tetra-acetylated histone H4 peptide from recombinant human N-terminal His-tagged BRD4 BD2 incubated for 2 hrs by TR-FRET assay	B	7.4	pIC50	40	nM	IC50	J Med Chem (2019) 62: 11080-11107 [PMID:31789032]
GtoPdb	Measured using a TR-FRET assay to evaluate binding to BD2 of BRD4.	-	7.4	pIC50	40	nM	IC50	PLoS ONE (2013) 8: e83190 [PMID:24391744]
bromodomain testis associated/Bromodomain testis-specific protein in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1795185] [GtoPdb: 2729] [UniProtKB: Q58F21]
ChEMBL	Binding affinity to recombinant BRDT BD1 (unknown origin) incubated for 1 hr by TR-FRET assay	B	5.32	pKd	4836	nM	Kd	J Med Chem (2020) 63: 5242-5256 [PMID:32255647]
ChEMBL	Binding affinity to recombinant BRDT BD2 (unknown origin) incubated for 1 hr by TR-FRET assay	B	6.15	pKd	708	nM	Kd	J Med Chem (2020) 63: 5242-5256 [PMID:32255647]
ChEMBL	Binding affinity BRDT BD1 (unknown origin) incubated for 1 hr by TR-FRET assay	B	5.3	pIC50	5027	nM	IC50	J Med Chem (2022) 65: 2388-2408 [PMID:34982556]
ChEMBL	Inhibition of BRDT BD1 (unknown origin) after 1 hr by TR-FRET assay	B	5.32	pIC50	4836	nM	IC50	Eur J Med Chem (2018) 151: 450-461 [PMID:29649741]
ChEMBL	Inhibition of BRDT BD2 (unknown origin) after 1 hr by TR-FRET assay	B	6.15	pIC50	708	nM	IC50	Eur J Med Chem (2018) 151: 450-461 [PMID:29649741]
ChEMBL	Binding affinity BRDT BD2 (unknown origin) incubated for 1 hr by TR-FRET assay	B	6.16	pIC50	696	nM	IC50	J Med Chem (2022) 65: 2388-2408 [PMID:34982556]
CREB binding protein/CREB-binding protein in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5747] [GtoPdb: 2734] [UniProtKB: Q92793]
ChEMBL	Binding affinity to recombinant CBP (unknown origin) incubated for 1 hr by TR-FRET assay	B	5	pKd	>10000	nM	Kd	J Med Chem (2020) 63: 5242-5256 [PMID:32255647]
ChEMBL	Inhibition of CBP (unknown origin) after 1 hr by TR-FRET assay	B	5	pIC50	>10000	nM	IC50	Eur J Med Chem (2018) 151: 450-461 [PMID:29649741]
ChEMBL	Binding affinity CBP (unknown origin) incubated for 1 hr by TR-FRET assay	B	5	pIC50	>10000	nM	IC50	J Med Chem (2022) 65: 2388-2408 [PMID:34982556]

ChEMBL data shown on this page come from version 32:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]