chlorpropamide [Ligand Id: 6801] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL498 (Chlorpropamide, Diabemide, Diabinese, Glucamide, Glymese, Melitase, NSC-44634, NSC-626720)
  • Organic anion transporter 1/Solute carrier family 22 member 6 in Rat [ChEMBL: CHEMBL1777665] [GtoPdb: 1025] [UniProtKB: O35956]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Organic anion transporter 1/Solute carrier family 22 member 6 in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1777665] [GtoPdb: 1025] [UniProtKB: O35956]
ChEMBL Inhibition of rat Oat1 expressed in Xenopus oocytes B 4.4 pKi 39500 nM Ki Bioorg. Med. Chem. (2011) 19: 3320-3340 [PMID:21571536]
ChEMBL TP_TRANSPORTER: inhibition of PAH uptake in Xenopus laevis oocytes F 4.4 pKi 39500 nM Ki Eur. J. Pharmacol. (2000) 398: 193-197 [PMID:10854830]

ChEMBL data shown on this page come from version 31:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]