EC18 [Ligand Id: 6262] activity data from GtoPdb

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  • HCN1 in Mouse [GtoPdb: 400] [UniProtKB: O88704]
Created with Highcharts 10.3.3ValuesChart context menuHCN1pKd MousepKi MousepIC50 MousepEC50 Mouse012345Highcharts.com
  • HCN2 in Mouse [GtoPdb: 401] [UniProtKB: O88703]
Created with Highcharts 10.3.3ValuesChart context menuHCN2pKd MousepKi MousepIC50 MousepEC50 Mouse012345Highcharts.com
  • HCN4 in Human [GtoPdb: 403] [UniProtKB: Q9Y3Q4]
Created with Highcharts 10.3.3ValuesChart context menuHCN4pKd HumanpKi HumanpIC50 HumanpEC50 Human0123456Highcharts.com
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
HCN1 in Mouse [GtoPdb: 400] [UniProtKB: O88704]
GtoPdb - - 4.68 pEC50 21000 nM EC50 Br J Pharmacol (2012) 166: 602-16 [PMID:22091830]
HCN2 in Mouse [GtoPdb: 401] [UniProtKB: O88703]
GtoPdb - - 4.71 pEC50 19350 nM EC50 Br J Pharmacol (2012) 166: 602-16 [PMID:22091830]
HCN4 in Human [GtoPdb: 403] [UniProtKB: Q9Y3Q4]
GtoPdb - - 5.4 pEC50 3980 nM EC50 Br J Pharmacol (2012) 166: 602-16 [PMID:22091830]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.