ChEMBL ligand: CHEMBL56
α1A-adrenoceptor/Alpha-1a adrenergic receptor in Human [ChEMBL: CHEMBL229] [GtoPdb: 22] [UniProtKB: P35348] Alpha-1a adrenergic receptor in Bovine [ChEMBL: CHEMBL4892] [UniProtKB: P18130] α1A-adrenoceptor/Alpha-1a adrenergic receptor in Rat [ChEMBL: CHEMBL319] [GtoPdb: 22] [UniProtKB: P43140] There should be some charts here, you may need to enable JavaScript!
α1B-adrenoceptor/Alpha-1b adrenergic receptor in Human [ChEMBL: CHEMBL232] [GtoPdb: 23] [UniProtKB: P35368] There should be some charts here, you may need to enable JavaScript!
α1D-adrenoceptor/Alpha-1d adrenergic receptor in Human [ChEMBL: CHEMBL223] [GtoPdb: 24] [UniProtKB: P25100] α1D-adrenoceptor/Alpha-1d adrenergic receptor in Rat [ChEMBL: CHEMBL326] [GtoPdb: 24] [UniProtKB: P23944] There should be some charts here, you may need to enable JavaScript!
Alpha-2a adrenergic receptor in Bovine [ChEMBL: CHEMBL4744] [UniProtKB: Q28838] There should be some charts here, you may need to enable JavaScript!
Dopamine D1 receptor in Bovine [ChEMBL: CHEMBL2967] [UniProtKB: Q95136] D1 receptor/Dopamine D1 receptor in Mouse [ChEMBL: CHEMBL3071] [GtoPdb: 214] [UniProtKB: Q61616] D1 receptor/Dopamine D1 receptor in Rat [ChEMBL: CHEMBL265] [GtoPdb: 214] [UniProtKB: P18901] There should be some charts here, you may need to enable JavaScript!
D2 receptor/Dopamine D2 receptor in Human [ChEMBL: CHEMBL217] [GtoPdb: 215] [UniProtKB: P14416] Dopamine D2 receptor in Bovine [ChEMBL: CHEMBL3998] [UniProtKB: P20288] D2 receptor/Dopamine D2 receptor in Rat [ChEMBL: CHEMBL339] [GtoPdb: 215] [UniProtKB: P61169] There should be some charts here, you may need to enable JavaScript!
D3 receptor/Dopamine D3 receptor in Human [ChEMBL: CHEMBL234] [GtoPdb: 216] [UniProtKB: P35462] D3 receptor/Dopamine D3 receptor in Rat [ChEMBL: CHEMBL3138] [GtoPdb: 216] [UniProtKB: P19020] There should be some charts here, you may need to enable JavaScript!
D4 receptor/Dopamine D4 receptor in Human [ChEMBL: CHEMBL219] [GtoPdb: 217] [UniProtKB: P21917] There should be some charts here, you may need to enable JavaScript!
DAT/Dopamine transporter in Rat [ChEMBL: CHEMBL338] [GtoPdb: 927] [UniProtKB: P23977] There should be some charts here, you may need to enable JavaScript!
Norepinephrine transporter in Rat [ChEMBL: CHEMBL304] [UniProtKB: Q9WTR4] There should be some charts here, you may need to enable JavaScript!
5-HT1A receptor/Serotonin 1a (5-HT1a) receptor in Human [ChEMBL: CHEMBL214] [GtoPdb: 1] [UniProtKB: P08908] 5-HT1A receptor/Serotonin 1a (5-HT1a) receptor in Rat [ChEMBL: CHEMBL273] [GtoPdb: 1] [UniProtKB: P19327] There should be some charts here, you may need to enable JavaScript!
5-HT1B receptor/Serotonin 1b (5-HT1b) receptor in Human [ChEMBL: CHEMBL1898] [GtoPdb: 2] [UniProtKB: P28222] 5-HT1B receptor/Serotonin 1b (5-HT1b) receptor in Rat [ChEMBL: CHEMBL3459] [GtoPdb: 2] [UniProtKB: P28564] There should be some charts here, you may need to enable JavaScript!
5-HT1D receptor/Serotonin 1d (5-HT1d) receptor in Human [ChEMBL: CHEMBL1983] [GtoPdb: 3] [UniProtKB: P28221] There should be some charts here, you may need to enable JavaScript!
Serotonin 2a (5-HT2a) receptor in Bovine [ChEMBL: CHEMBL3446] [UniProtKB: Q75Z89] 5-HT2A receptor/Serotonin 2a (5-HT2a) receptor in Rat [ChEMBL: CHEMBL322] [GtoPdb: 6] [UniProtKB: P14842] There should be some charts here, you may need to enable JavaScript!
5-HT2C receptor/Serotonin 2c (5-HT2c) receptor in Human [ChEMBL: CHEMBL225] [GtoPdb: 8] [UniProtKB: P28335] There should be some charts here, you may need to enable JavaScript!
5-HT3A/5-HT3B/Serotonin 3 (5-HT3) receptor in Rat [ChEMBL: CHEMBL2094116] [GtoPdb: 373, 374] [UniProtKB: P35563, Q9JJ16] There should be some charts here, you may need to enable JavaScript!
5-HT5A receptor/Serotonin 5a (5-HT5a) receptor in Human [ChEMBL: CHEMBL3426] [GtoPdb: 10] [UniProtKB: P47898] There should be some charts here, you may need to enable JavaScript!
5-HT6 receptor/Serotonin 6 (5-HT6) receptor in Human [ChEMBL: CHEMBL3371] [GtoPdb: 11] [UniProtKB: P50406] There should be some charts here, you may need to enable JavaScript!
5-HT7 receptor/Serotonin 7 (5-HT7) receptor in Human [ChEMBL: CHEMBL3155] [GtoPdb: 12] [UniProtKB: P34969] 5-HT7 receptor/Serotonin 7 (5-HT7) receptor in Rat [ChEMBL: CHEMBL3223] [GtoPdb: 12] [UniProtKB: P32305] There should be some charts here, you may need to enable JavaScript!
SERT/Serotonin transporter in Rat [ChEMBL: CHEMBL313] [GtoPdb: 928] [UniProtKB: P31652] There should be some charts here, you may need to enable JavaScript!
sigma non-opioid intracellular receptor 1/Sigma opioid receptor in Human [ChEMBL: CHEMBL287] [GtoPdb: 2552] [UniProtKB: Q99720] sigma non-opioid intracellular receptor 1/Sigma opioid receptor in Rat [ChEMBL: CHEMBL3602] [GtoPdb: 2552] [UniProtKB: Q9R0C9] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
α1A-adrenoceptor/Alpha-1a adrenergic receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL229] [GtoPdb: 22] [UniProtKB: P35348]
ChEMBL	Binding affinity towards human cloned alpha-1A-adrenoceptor using [3H]prazosin as radioligand	B	5.76	pKi	1757.2	nM	Ki	J Med Chem (2001) 44: 2403-2410 [PMID:11448222]
ChEMBL	Binding affinity was determined on human cloned Alpha-1A adrenoceptor	B	5.76	pKi	1757	nM	Ki	J Med Chem (2001) 44: 4431-4442 [PMID:11728188]
ChEMBL	The binding affinity was evaluated on cloned human alpha-1A adrenergic receptor expressed in chinese hamster ovary(CHO) cells by using [3H]prazosin as radioligand.	B	6	pKi	<6	nM	Log Ki	J Med Chem (1999) 42: 2961-2968 [PMID:10425105]
ChEMBL	Displacement of [3H]prazosin from human cloned Alpha-1A adrenergic receptor	B	6	pKi	<1000	nM	Ki	J Med Chem (1999) 42: 4214-4224 [PMID:10514291]
ChEMBL	Displacement of [3H]prazosin from human cloned alpha1A adrenoceptor expressed in CHO cells	B	6	pKi	>1000	nM	Ki	J Med Chem (2008) 51: 6359-6370 [PMID:18817363]
ChEMBL	Displacement of [3H]prazosin from human recombinant alpha1A adrenergic receptor expressed in CHO cell membranes after 30 mins	B	6	pKi	>1000	nM	Ki	J Med Chem (2013) 56: 584-588 [PMID:23252794]
ChEMBL	Displacement of [3H]Prazosin from human recombinant alpha 1A adrenergic receptor expressed in CHO cells incubated for 30 mins by radioligand competition binding assay	B	6	pKi	>1000	nM	Ki	Eur J Med Chem (2019) 168: 461-473 [PMID:30844609]
ChEMBL	Displacement of [3H]prazosin from human alpha1A adrenergic receptor expressed in CHO cells	B	6.82	pKi	151.36	nM	Ki	Bioorg Med Chem Lett (2010) 20: 2017-2020 [PMID:20185311]
ChEMBL	Displacement of [3H]prazosin from human recombinant alpha1A adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting	B	6.82	pKi	151.36	nM	Ki	J Med Chem (2012) 55: 23-36 [PMID:22145629]
Alpha-1a adrenergic receptor in Bovine (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4892] [UniProtKB: P18130]
ChEMBL	Binding affinity against alpha-1 adrenergic receptor in calf frontal cortex	B	4.52	pIC50	30000	nM	IC50	J Med Chem (1994) 37: 1779-1793 [PMID:7912735]
α1A-adrenoceptor/Alpha-1a adrenergic receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL319] [GtoPdb: 22] [UniProtKB: P43140]
ChEMBL	In vitro binding affinity towards alpha-1A adrenergic receptor through displacement of [3H]prazosin in epididymal rat vas deferens.	B	5.68	pKi	2082	nM	Ki	J Med Chem (2004) 47: 1900-1918 [PMID:15055991]
α1B-adrenoceptor/Alpha-1b adrenergic receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL232] [GtoPdb: 23] [UniProtKB: P35368]
ChEMBL	Binding affinity towards human cloned alpha-1B-adrenoceptor using [3H]prazosin as radioligand	B	5.22	pKi	5975	nM	Ki	J Med Chem (2001) 44: 2403-2410 [PMID:11448222]
ChEMBL	Binding affinity was determined on human cloned alpha-1B adrenergic receptor	B	5.22	pKi	5975	nM	Ki	J Med Chem (2001) 44: 4431-4442 [PMID:11728188]
ChEMBL	Binding affinity constant against alpha-1B adrenergic receptor of guinea pig spleen	B	5.73	pKi	1882	nM	Ki	J Med Chem (2004) 47: 1900-1918 [PMID:15055991]
ChEMBL	The binding affinity was evaluated on cloned human alpha-1B adrenergic receptor expressed in chinese hamster ovary(CHO) cells by using [3H]prazosin as radioligand.	B	6	pKi	<6	nM	Log Ki	J Med Chem (1999) 42: 2961-2968 [PMID:10425105]
ChEMBL	Displacement of [3H]prazosin from human recombinant alpha1B adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting	B	6	pKi	>1000	nM	Ki	J Med Chem (2012) 55: 23-36 [PMID:22145629]
ChEMBL	Displacement of [3H]prazosin from human recombinant alpha1B adrenergic receptor expressed in CHO cell membranes after 30 mins	B	6	pKi	>1000	nM	Ki	J Med Chem (2013) 56: 584-588 [PMID:23252794]
ChEMBL	Displacement of [3H]prazosin from human cloned Alpha-1B adrenergic receptor	B	6	pKi	<1000	nM	Ki	J Med Chem (1999) 42: 4214-4224 [PMID:10514291]
ChEMBL	Displacement of [3H]Prazosin from human recombinant alpha 1B adrenergic receptor expressed in CHO cells incubated for 30 mins by radioligand competition binding assay	B	6	pKi	>1000	nM	Ki	Eur J Med Chem (2019) 168: 461-473 [PMID:30844609]
ChEMBL	Displacement of [3H]prazosin from human cloned Alpha-1B adrenoceptor expressed in CHO cells	B	6	pKi	>1000	nM	Ki	J Med Chem (2008) 51: 6359-6370 [PMID:18817363]
ChEMBL	Displacement of [3H]prazosin from human Alpha-1B adrenergic receptor expressed in CHO cells	B	6	pKi	>1000	nM	Ki	Bioorg Med Chem Lett (2010) 20: 2017-2020 [PMID:20185311]
α1D-adrenoceptor/Alpha-1d adrenergic receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL223] [GtoPdb: 24] [UniProtKB: P25100]
ChEMBL	The binding affinity was evaluated on cloned human alpha-1D adrenergic receptor expressed in chinese hamster ovary(CHO) cells by using [3H]prazosin as radioligand.	B	6	pKi	<6	nM	Log Ki	J Med Chem (1999) 42: 2961-2968 [PMID:10425105]
ChEMBL	Displacement of [3H]prazosin from human cloned Alpha-1D adrenergic receptor	B	6	pKi	<1000	nM	Ki	J Med Chem (1999) 42: 4214-4224 [PMID:10514291]
ChEMBL	Binding affinity towarda alpha-1D adrenergic receptor	B	6	pKi	>1000	nM	Ki	J Med Chem (2001) 44: 4431-4442 [PMID:11728188]
ChEMBL	Binding affinity towards human cloned alpha-1D-adrenoceptor using [3H]prazosin as radioligand	B	6	pKi	>1000	nM	Ki	J Med Chem (2001) 44: 2403-2410 [PMID:11448222]
ChEMBL	Displacement of [3H]prazosin from human cloned alpha1D adrenoceptor expressed in CHO cells	B	6	pKi	>1000	nM	Ki	J Med Chem (2008) 51: 6359-6370 [PMID:18817363]
ChEMBL	Displacement of [3H]prazosin from human Alpha-1D adrenergic receptor expressed in CHO cells	B	6	pKi	>1000	nM	Ki	Bioorg Med Chem Lett (2010) 20: 2017-2020 [PMID:20185311]
ChEMBL	Displacement of [3H]prazosin from human recombinant Alpha-1D adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting	B	6	pKi	>1000	nM	Ki	J Med Chem (2012) 55: 23-36 [PMID:22145629]
ChEMBL	Displacement of [3H]prazosin from human recombinant alpha1D adrenergic receptor expressed in CHO cell membranes after 30 mins	B	6	pKi	>1000	nM	Ki	J Med Chem (2013) 56: 584-588 [PMID:23252794]
ChEMBL	Displacement of [3H]Prazosin from human recombinant alpha 1D adrenergic receptor expressed in CHO cells incubated for 30 mins by radioligand competition binding assay	B	6	pKi	>1000	nM	Ki	Eur J Med Chem (2019) 168: 461-473 [PMID:30844609]
α1D-adrenoceptor/Alpha-1d adrenergic receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL326] [GtoPdb: 24] [UniProtKB: P23944]
ChEMBL	Binding affinity to the adrenergic receptor alpha-1D of rat aorta	B	5.27	pKi	5421	nM	Ki	J Med Chem (2004) 47: 1900-1918 [PMID:15055991]
Alpha-2a adrenergic receptor in Bovine (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4744] [UniProtKB: Q28838]
ChEMBL	Binding affinity against alpha-2 adrenergic receptor in calf frontal cortex	B	6	pIC50	1000	nM	IC50	J Med Chem (1994) 37: 1779-1793 [PMID:7912735]
Dopamine D1 receptor in Bovine (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2967] [UniProtKB: Q95136]
ChEMBL	Inhibition of [3H]SCH-23390 binding to Dopamine receptor D1 of bovine striatum	B	4.06	pKi	87300	nM	Ki	J Med Chem (1997) 40: 952-960 [PMID:9083484]
D1 receptor/Dopamine D1 receptor in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3071] [GtoPdb: 214] [UniProtKB: Q61616]
ChEMBL	Binding affinity against Dopamine receptor D1	B	6	pKi	>1000	nM	Ki	J Med Chem (1997) 40: 952-960 [PMID:9083484]
D1 receptor/Dopamine D1 receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL265] [GtoPdb: 214] [UniProtKB: P18901]
ChEMBL	In vitro binding activity against dopamine D1 receptor from homogenized rat brain, using [3H]SCH-23390 as the radioligand	B	4	pIC50	>100000	nM	IC50	J Med Chem (1989) 32: 2273-2276 [PMID:2571729]
D2 receptor/Dopamine D2 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL217] [GtoPdb: 215] [UniProtKB: P14416]
ChEMBL	Inhibitory activity against [125I]- NCQ298 binding to dopamine receptor D2 in Sf 9 cells	B	5.49	pKi	3243	nM	Ki	J Med Chem (1993) 36: 3161-3165 [PMID:8230102]
ChEMBL	Binding affinity against [3H]U-86,170-labeled dopamine receptor D2 in cloned CHO cells	B	7.07	pKi	86	nM	Ki	J Med Chem (1993) 36: 1053-1068 [PMID:8097537]
ChEMBL	Binding affinity against [3H]U-86,170-labeled dopamine receptor D2 in cloned CHO cells	B	7.07	pKi	86	nM	Ki	J Med Chem (1993) 36: 1069-1083 [PMID:8097538]
ChEMBL	Binding affinity against Dopamine receptor D2	B	7.08	pKi	84	nM	Ki	J Med Chem (1997) 40: 952-960 [PMID:9083484]
ChEMBL	Inhibitory concentration against binding of Dopamine receptor D2 by displacement of [3H]spiperone	B	6	pIC50	>1000	nM	IC50	Bioorg Med Chem Lett (2000) 10: 509-512 [PMID:10743959]
Dopamine D2 receptor in Bovine (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3998] [UniProtKB: P20288]
ChEMBL	Inhibition of [3H]raclopride binding to Dopamine receptor D2 of bovine striatum	B	5.62	pKi	2380	nM	Ki	J Med Chem (1997) 40: 952-960 [PMID:9083484]
ChEMBL	Compound was evaluated for the binding affinity towards Dopamine receptor D2 using [3H]raclopride radioligand.	B	6.1	pIC50	800	nM	IC50	J Med Chem (1996) 39: 4285-4298 [PMID:8863806]
ChEMBL	Binding affinity against D2 receptor in calf caudate nucleus	B	6.1	pIC50	800	nM	IC50	J Med Chem (1994) 37: 1779-1793 [PMID:7912735]
D2 receptor/Dopamine D2 receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL339] [GtoPdb: 215] [UniProtKB: P61169]
ChEMBL	Binding affinity of compound against Dopamine receptor D2 binding site using radioligand [3H]spiperone	B	5.46	pKi	3500	nM	Ki	J Med Chem (1989) 32: 1959-1962 [PMID:2569041]
ChEMBL	Binding affinity against D2 receptor in homogenated rat brain tissue, using by [3H]spiperone as radioligand	B	5.87	pKi	1357	nM	Ki	J Med Chem (1993) 36: 3409-3416 [PMID:8230131]
ChEMBL	Displacement of [3H]spiperone from dopamine receptor D2	B	5.87	pKi	1357	nM	Ki	J Med Chem (1993) 36: 2059-2065 [PMID:8340910]
ChEMBL	Displacement of the radioligand [3H]spiperone from D2 receptor	B	5.87	pKi	1357	nM	Ki	J Med Chem (1994) 37: 3263-3273 [PMID:7932553]
ChEMBL	Binding affinity against Dopamine receptor D2 from CHO-K1 cells, using [3H]U-86,170 as the radioligand.	B	5.95	pKi	1126	nM	Ki	J Med Chem (1995) 38: 2202-2216 [PMID:7783152]
ChEMBL	The binding affinity was evaluated on Dopamine receptor D2 expressed in rat striatum by using [3H]spiperone as radioligand	B	6	pKi	<6	nM	Log Ki	J Med Chem (1999) 42: 2961-2968 [PMID:10425105]
ChEMBL	Binding affinity against [3H]raclopride-labeled dopamine receptor D2 in rat striatum.	B	6	pKi	>1000	nM	Ki	J Med Chem (1993) 36: 1053-1068 [PMID:8097537]
ChEMBL	Displacement of [3H]spiperone from rat brain Dopamine receptor D2	B	6	pKi	<1000	nM	Ki	J Med Chem (1999) 42: 4214-4224 [PMID:10514291]
ChEMBL	Binding affinity for [3H]raclopride-labeled dopamine receptor D2 in rat striatum	B	6	pKi	>1000	nM	Ki	J Med Chem (1993) 36: 1069-1083 [PMID:8097538]
ChEMBL	Displacement of [3H]YM-09151-2 from rat striatum D2 receptor	B	6.26	pKi	549.54	nM	Ki	J Med Chem (2007) 50: 865-876 [PMID:17300168]
ChEMBL	Displacement of [3H]U-86170 from Dopamine receptor D2	B	7.07	pKi	86	nM	Ki	J Med Chem (1995) 38: 725-734 [PMID:7861420]
ChEMBL	Tested in vitro for the inhibition of [3H]raclopride binding to Dopamine receptor D2 in rat striatum	B	7.07	pKi	86	nM	Ki	Bioorg Med Chem Lett (1997) 7: 2759-2764
ChEMBL	The compound was tested in vitro for inhibitory activity against dopamine receptor in rats using [3H]spiperone as radioligand	B	5.24	pIC50	5800	nM	IC50	J Med Chem (1992) 35: 3984-3990 [PMID:1433207]
ChEMBL	In vitro binding activity against Dopamine receptor D2 from homogenized rat brain, using [3H]spiperone as the radioligand	B	5.24	pIC50	5760	nM	IC50	J Med Chem (1989) 32: 2273-2276 [PMID:2571729]
ChEMBL	Binding affinity to rat Dopamine receptor D2 expressed in CHO cells was determined using [125 I ] iodosulpride as radioligand	B	8.28	pIC50	5.2	nM	IC50	J Med Chem (1996) 39: 3195-3202 [PMID:8759642]
ChEMBL	Binding affinity towards rat Dopamine receptor D2 was evaluated using [3H]- spiroperidol as radioligand	B	8.28	pIC50	5.2	nM	IC50	J Med Chem (1996) 39: 4928-4934 [PMID:8960552]
D3 receptor/Dopamine D3 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL234] [GtoPdb: 216] [UniProtKB: P35462]
ChEMBL	Inhibition of [3H]spiperone binding to Dopamine receptor D3 in bovine cortex	B	4.84	pKi	14600	nM	Ki	J Med Chem (1997) 40: 952-960 [PMID:9083484]
ChEMBL	Tested in vitro for the inhibition of [3H]U-86170 binding to Dopamine receptor D3, expressed in cloned CHO cells	B	6.59	pKi	259	nM	Ki	Bioorg Med Chem Lett (1997) 7: 2759-2764
D3 receptor/Dopamine D3 receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3138] [GtoPdb: 216] [UniProtKB: P19020]
ChEMBL	Binding affinity against Dopamine receptor D3 from CHO-K1 cells, using [3H]spiperone as the radioligand.	B	6.48	pKi	333	nM	Ki	J Med Chem (1995) 38: 2202-2216 [PMID:7783152]
ChEMBL	Inhibitory activity against [125I]- NCQ298 binding to dopamine receptor D3 in Sf 9 cells	B	6.6	pKi	251	nM	Ki	J Med Chem (1993) 36: 3161-3165 [PMID:8230102]
ChEMBL	Tested for binding affinity against dopamine receptor D3 expressed in Sf9 cells.	B	6.61	pKi	248	nM	Ki	J Med Chem (1993) 36: 1499-1500 [PMID:8098771]
D4 receptor/Dopamine D4 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL219] [GtoPdb: 217] [UniProtKB: P21917]
ChEMBL	Tested in vitro for the inhibition of [3H]spiperone binding to Dopamine receptor D4, expressed in cloned CHO cells	B	5.82	pKi	>1515	nM	Ki	Bioorg Med Chem Lett (1997) 7: 2759-2764
DAT/Dopamine transporter in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL338] [GtoPdb: 927] [UniProtKB: P23977]
ChEMBL	Binding affinity against dopamine transporter (DAT) by displacement of [3H]WIN-35428 in male wistar rats	B	6	pIC50	>1000	nM	IC50	J Med Chem (2003) 46: 5512-5532 [PMID:14640559]
Norepinephrine transporter in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL304] [UniProtKB: Q9WTR4]
ChEMBL	Binding affinity against norepinephrine transporter (NET) by displacement of [3H]nisoxetine in male wistar rats	B	6	pIC50	>1000	nM	IC50	J Med Chem (2003) 46: 5512-5532 [PMID:14640559]
5-HT1A receptor/Serotonin 1a (5-HT1a) receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL214] [GtoPdb: 1] [UniProtKB: P08908]
GtoPdb	-	-	9.4	pKd	0.4	nM	Kd	Naunyn Schmiedebergs Arch Pharmacol (1999) 359: 447-53 [PMID:10431754]; Naunyn Schmiedebergs Arch Pharmacol (1998) 357: 205-17 [PMID:9550290]; Biosci Rep (2004) 24: 101-15 [PMID:15628665]; J Med Chem (2000) 43: 4701-10 [PMID:11101361]
ChEMBL	Displacement of [3H]WAY100635 from human recombinant 5HT1A receptor	B	5.4	pKi	3981.07	nM	Ki	J Med Chem (2008) 51: 2887-2890 [PMID:18433113]
ChEMBL	Displacement of [3H]8-OH-DPAT from human cloned 5-HT1A receptor expressed in human HeLa cells	B	5.48	pKi	3300	nM	Ki	J Med Chem (2008) 51: 7602-7613 [PMID:19053888]
ChEMBL	Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells after 120 mins	B	8.29	pKi	5.1	nM	Ki	J Med Chem (2008) 51: 1492-1495 [PMID:18269229]
ChEMBL	Binding affinity to human 5-hydroxytryptamine 1A receptor was measured using [3H]-8-hydroxy-2-(di-n-propylamine) tetraline [3H]8-OH-DPAT) as radioligand	B	8.42	pKi	3.8	nM	Ki	J Med Chem (2004) 47: 1900-1918 [PMID:15055991]
ChEMBL	Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor expressed in human HeLa cells