ChEMBL ligand: CHEMBL56564 (ICS-205-930, Navoban, Novaban, NSC-759842, SDZ-ICS-930, Tropisetron, Tropisetron (as hydrochloride), Tropisetron hcl, Tropisetron hydrochloride, Tropisetron monohydrochloride)
nicotinic acetylcholine receptor α1 subunit/nicotinic acetylcholine receptor γ subunit/nicotinic acetylcholine receptor β1 subunit/nicotinic acetylcholine receptor δ subunit/Acetylcholine receptor; alpha1/beta1/delta/gamma in Human [ChEMBL: CHEMBL1907588] [GtoPdb: 462, 475, 471, 476] [UniProtKB: P02708, P07510, P11230, Q07001] There should be some charts here, you may need to enable JavaScript!
D2 receptor/Dopamine D2 receptor in Rat [ChEMBL: CHEMBL339] [GtoPdb: 215] [UniProtKB: P61169] There should be some charts here, you may need to enable JavaScript!
M5 receptor/Muscarinic acetylcholine receptor M5 in Human [ChEMBL: CHEMBL2035] [GtoPdb: 17] [UniProtKB: P08912] There should be some charts here, you may need to enable JavaScript!
nicotinic acetylcholine receptor β4 subunit/nicotinic acetylcholine receptor α3 subunit/Neuronal acetylcholine receptor; alpha3/beta4 in Human [ChEMBL: CHEMBL1907594] [GtoPdb: 474, 464] [UniProtKB: P30926, P32297] There should be some charts here, you may need to enable JavaScript!
nicotinic acetylcholine receptor β2 subunit/nicotinic acetylcholine receptor α4 subunit/Neuronal acetylcholine receptor; alpha4/beta2 in Human [ChEMBL: CHEMBL1907589] [GtoPdb: 472, 465] [UniProtKB: P17787, P43681] There should be some charts here, you may need to enable JavaScript!
nicotinic acetylcholine receptor α7 subunit/Neuronal acetylcholine receptor protein alpha-7 subunit in Human [ChEMBL: CHEMBL2492] [GtoPdb: 468] [UniProtKB: P36544] nicotinic acetylcholine receptor α7 subunit/Neuronal acetylcholine receptor protein alpha-7 subunit in Mouse [ChEMBL: CHEMBL3365] [GtoPdb: 468] [UniProtKB: P49582] nicotinic acetylcholine receptor α7 subunit/Neuronal acetylcholine receptor protein alpha-7 subunit in Rat [ChEMBL: CHEMBL4980] [GtoPdb: 468] [UniProtKB: Q05941] There should be some charts here, you may need to enable JavaScript!
nicotinic acetylcholine receptor α3 subunit/Neuronal acetylcholine receptor subunit alpha-3 in Human [ChEMBL: CHEMBL3068] [GtoPdb: 464] [UniProtKB: P32297] There should be some charts here, you may need to enable JavaScript!
5-HT1A receptor/Serotonin 1a (5-HT1a) receptor in Human [ChEMBL: CHEMBL214] [GtoPdb: 1] [UniProtKB: P08908] There should be some charts here, you may need to enable JavaScript!
5-HT3E/5-HT3B/5-HT3A/5-HT3D/5-HT3C/Serotonin 3 (5-HT3) receptor in Human [ChEMBL: CHEMBL2094132] [GtoPdb: 377, 374, 373, 376, 375] [UniProtKB: A5X5Y0, O95264, P46098, Q70Z44, Q8WXA8] 5-HT3A/5-HT3B/Serotonin 3 (5-HT3) receptor in Rat [ChEMBL: CHEMBL2094116] [GtoPdb: 373, 374] [UniProtKB: P35563, Q9JJ16] There should be some charts here, you may need to enable JavaScript!
5-HT3A/Serotonin 3a (5-HT3a) receptor in Human [ChEMBL: CHEMBL1899] [GtoPdb: 373] [UniProtKB: P46098] Serotonin 3a (5-HT3a) receptor in Guinea pig [ChEMBL: CHEMBL3666] [UniProtKB: O70212] There should be some charts here, you may need to enable JavaScript!
5-HT4 receptor/Serotonin 4 (5-HT4) receptor in Human [ChEMBL: CHEMBL1875] [GtoPdb: 9] [UniProtKB: Q13639] 5-HT4 receptor/Serotonin 4 (5-HT4) receptor in Mouse [ChEMBL: CHEMBL2183] [GtoPdb: 9] [UniProtKB: P97288] 5-HT4 receptor/Serotonin 4 (5-HT4) receptor in Rat [ChEMBL: CHEMBL4317] [GtoPdb: 9] [UniProtKB: Q62758] Serotonin 4 (5-HT4) receptor in Guinea pig [ChEMBL: CHEMBL5017] [UniProtKB: O70528] There should be some charts here, you may need to enable JavaScript!
SERT/Serotonin transporter in Human [ChEMBL: CHEMBL228] [GtoPdb: 928] [UniProtKB: P31645] There should be some charts here, you may need to enable JavaScript!
5-HT3A in Human [GtoPdb: 379] There should be some charts here, you may need to enable JavaScript!
glycine receptor α1 subunit in Human [GtoPdb: 423] [UniProtKB: P23415] There should be some charts here, you may need to enable JavaScript!
glycine receptor α2 subunit in Human [GtoPdb: 424] [UniProtKB: P23416] There should be some charts here, you may need to enable JavaScript!
glycine receptor β subunit in Human [GtoPdb: 427] [UniProtKB: P48167] There should be some charts here, you may need to enable JavaScript!
Glycine Receptor (All subtypes) in Human [GtoPdb: 428] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
nicotinic acetylcholine receptor α1 subunit/nicotinic acetylcholine receptor γ subunit/nicotinic acetylcholine receptor β1 subunit/nicotinic acetylcholine receptor δ subunit/Acetylcholine receptor; alpha1/beta1/delta/gamma in Human (target type: PROTEIN COMPLEX) [ChEMBL: CHEMBL1907588] [GtoPdb: 462, 475, 471, 476] [UniProtKB: P02708, P07510, P11230, Q07001]
ChEMBL	In vitro Binding affinity towards alpha-1-beta-1-gamma-delta nAChR was determined	B	4.57	pKi	27000	nM	Ki	Bioorg Med Chem Lett (2001) 11: 319-321 [PMID:11212100]
D2 receptor/Dopamine D2 receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL339] [GtoPdb: 215] [UniProtKB: P61169]
ChEMBL	Binding affinity towards Dopamine receptor D2 in rat was evaluated	B	6	pIC50	>1000	nM	IC50	Bioorg Med Chem Lett (2002) 12: 189-192 [PMID:11755351]
M5 receptor/Muscarinic acetylcholine receptor M5 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2035] [GtoPdb: 17] [UniProtKB: P08912]
ChEMBL	DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine)	B	5.61	pKi	2479	nM	Ki	DrugMatrix in vitro pharmacology data
ChEMBL	DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine)	B	5.46	pIC50	3450	nM	IC50	DrugMatrix in vitro pharmacology data
nicotinic acetylcholine receptor β4 subunit/nicotinic acetylcholine receptor α3 subunit/Neuronal acetylcholine receptor; alpha3/beta4 in Human (target type: PROTEIN COMPLEX) [ChEMBL: CHEMBL1907594] [GtoPdb: 474, 464] [UniProtKB: P30926, P32297]
ChEMBL	Antagonism of ACh-evoked responses at human Nicotinic acetylcholine receptor alpha3-beta4 expressed in xenopus oocytes	F	5.74	pIC50	1800	nM	IC50	Bioorg Med Chem Lett (2004) 14: 1849-1853 [PMID:15050614]
nicotinic acetylcholine receptor β2 subunit/nicotinic acetylcholine receptor α4 subunit/Neuronal acetylcholine receptor; alpha4/beta2 in Human (target type: PROTEIN COMPLEX) [ChEMBL: CHEMBL1907589] [GtoPdb: 472, 465] [UniProtKB: P17787, P43681]
ChEMBL	In vitro Binding affinity towards Nicotinic acetylcholine receptor alpha4-beta2 was determined	B	4.26	pKi	55000	nM	Ki	Bioorg Med Chem Lett (2001) 11: 319-321 [PMID:11212100]
nicotinic acetylcholine receptor α7 subunit/Neuronal acetylcholine receptor protein alpha-7 subunit in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2492] [GtoPdb: 468] [UniProtKB: P36544]
ChEMBL	Inhibition constant against nicotinic acetylcholine receptor alpha7	B	8.16	pKi	6.9	nM	Ki	J Med Chem (2005) 48: 6523-6543 [PMID:16220969]
ChEMBL	Binding affinity to alpha7 nAChR	B	8.16	pKi	6.9	nM	Ki	J Med Chem (2011) 54: 7943-7961 [PMID:21919481]
ChEMBL	Effective concentration that causes inhibition of alpha-7 nAChR, was determined. Values are expressed as EC50 +/- SEM.	F	5.89	pEC50	1300	nM	EC50	Bioorg Med Chem Lett (2001) 11: 319-321 [PMID:11212100]
ChEMBL	Agonist activity at alpha7 nAChR	F	5.89	pEC50	1300	nM	EC50	J Med Chem (2011) 54: 7943-7961 [PMID:21919481]
nicotinic acetylcholine receptor α7 subunit/Neuronal acetylcholine receptor protein alpha-7 subunit in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3365] [GtoPdb: 468] [UniProtKB: P49582]
ChEMBL	In vitro Binding affinity towards alpha-7 nAChR was determined	B	8.16	pKi	6.9	nM	Ki	Bioorg Med Chem Lett (2001) 11: 319-321 [PMID:11212100]
nicotinic acetylcholine receptor α7 subunit/Neuronal acetylcholine receptor protein alpha-7 subunit in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4980] [GtoPdb: 468] [UniProtKB: Q05941]
ChEMBL	Partial agonist activity at rat alpha-7 nicotinic acetylcholine receptor expressed in Xenopus oocytes assessed as induction of currents	B	5.89	pEC50	1300	nM	EC50	Bioorg Med Chem Lett (2015) 25: 3184-3188 [PMID:26087938]
ChEMBL	Activation responses to that evoked by ACh at human Nicotinic acetylcholine receptor alpha-7 expressed in xenopus oocytes	B	8	pEC50	10	nM	EC50	Bioorg Med Chem Lett (2004) 14: 1849-1853 [PMID:15050614]
nicotinic acetylcholine receptor α3 subunit/Neuronal acetylcholine receptor subunit alpha-3 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3068] [GtoPdb: 464] [UniProtKB: P32297]
ChEMBL	In vitro Binding affinity towards alpha-3 (PC12) nAChR was determined	B	4.8	pKi	16000	nM	Ki	Bioorg Med Chem Lett (2001) 11: 319-321 [PMID:11212100]
5-HT1A receptor/Serotonin 1a (5-HT1a) receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL214] [GtoPdb: 1] [UniProtKB: P08908]
ChEMBL	Inhibition constant against 5-hydroxytryptamine 1A receptor	B	8.28	pKi	5.3	nM	Ki	J Med Chem (2005) 48: 6523-6543 [PMID:16220969]
5-HT3E/5-HT3B/5-HT3A/5-HT3D/5-HT3C/Serotonin 3 (5-HT3) receptor in Human (target type: PROTEIN COMPLEX GROUP) [ChEMBL: CHEMBL2094132] [GtoPdb: 377, 374, 373, 376, 375] [UniProtKB: A5X5Y0, O95264, P46098, Q70Z44, Q8WXA8]
ChEMBL	Binding affinity to 5-hydroxytryptamine 3 receptor entirely in guinea pig ileum	B	7.9	pKd	12.59	nM	Kd	J Med Chem (1990) 33: 1594-1600 [PMID:2342053]
ChEMBL	Antagonistic activity against Serotonin 5-hydroxytryptamine 3 receptor of isolated guinea pig ileum (GPI)	F	7.9	pKd	12.59	nM	Kd	Bioorg Med Chem Lett (1992) 2: 461-466
ChEMBL	Binding affinity to 5-hydroxytryptamine 3 receptor of neuronal in the afferent rabbit vagus	B	10.2	pKd	0.06	nM	Kd	J Med Chem (1990) 33: 1594-1600 [PMID:2342053]
ChEMBL	Antagonistic activity against Serotonin 5-hydroxytryptamine 3 receptor in isolated rabbit vagus nerve (RVN)	F	10.2	pKd	0.06	nM	Kd	Bioorg Med Chem Lett (1992) 2: 461-466
ChEMBL	Evaluated for the antagonistic activity against Serotonin 5-hydroxytryptamine 3 receptor in isolated perfused rabbit heart (RH)	F	10.6	pKd	0.03	nM	Kd	Bioorg Med Chem Lett (1992) 2: 461-466
ChEMBL	Binding affinity of compound towards 5-hydroxytryptamine 3 receptor using [3H]-BRL-43694 (1 nM) ligand in NG cells 108-15 was determined	B	7.48	pKi	33	nM	Ki	J Med Chem (1997) 40: 952-960 [PMID:9083484]
ChEMBL	In vitro Binding affinity towards 5-hydroxytryptamine 3 receptor was determined	B	8.28	pKi	5.3	nM	Ki	Bioorg Med Chem Lett (2001) 11: 319-321 [PMID:11212100]
5-HT3A/5-HT3B/Serotonin 3 (5-HT3) receptor in Rat (target type: PROTEIN COMPLEX) [ChEMBL: CHEMBL2094116] [GtoPdb: 373, 374] [UniProtKB: P35563, Q9JJ16]
ChEMBL	Compound was evaluated for its binding affinity for 5-hydroxytryptamine 3 receptor by measuring displacement [3H]GR-65630 in rat cerebral cortex	B	8.49	pKi	3.2	nM	Ki	J Med Chem (1998) 41: 311-317 [PMID:9464362]
ChEMBL	Binding affinity to 5-hydroxytryptamine 3 receptor using [3H]GR-65630 as radioligand in rat cortex	B	8.5	pKi	3.16	nM	Ki	J Med Chem (1990) 33: 1594-1600 [PMID:2342053]
ChEMBL	In vitro displacement of [3H]ICS-205-930 from 5-hydroxytryptamine 3 receptor in cultured NG-108-15 rat glioma cells	B	8.57	pKi	2.7	nM	Ki	J Med Chem (1990) 33: 13-16 [PMID:2296012]
ChEMBL	Binding affinity against 5-hydroxytryptamine 3 (5-HT3) receptor in rat brain cortical membranes using radioligand [3H]quipazine	B	8.7	pKi	2	nM	Ki	J Med Chem (1993) 36: 2645-2657 [PMID:8410977]
ChEMBL	Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex	B	8.77	pKi	1.71	nM	Ki	J Med Chem (1990) 33: 2101-2108 [PMID:1695682]
ChEMBL	In vitro by displacement of [3H]LY-278584 from 5-hydroxytryptamine 3 receptor on rat entorhinal cortex	B	8.8	pKi	1.58	nM	Ki	J Med Chem (1997) 40: 586-593 [PMID:9046349]
ChEMBL	In vitro affinity for 5-hydroxytryptamine 3 (5-HT3) receptor by displacement of [3H]BRL-43694 from rat entorhinal cortex	B	8.8	pKi	1.57	nM	Ki	J Med Chem (1997) 40: 3369-3380 [PMID:9341912]
ChEMBL	Binding affinity towards rat 5-hydroxytryptamine 3 receptor was evaluated	B	8.81	pKi	1.55	nM	Ki	Bioorg Med Chem Lett (2002) 12: 189-192 [PMID:11755351]
ChEMBL	pKi value for inhibition of [3H]LY-278584 binding to 5-hydroxytryptamine 3 receptor	B	8.89	pKi	1.29	nM	Ki	J Med Chem (1990) 33: 3176-3181 [PMID:2258903]
ChEMBL	Inhibitory activity against 5-hydroxytryptamine 3 receptor in rat cortical membranes using [3H]- 1-Methyl-1H-indazole-3-carboxylic acid (8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-amide as a radioligand	B	8.89	pKi	1.28	nM	Ki	J Med Chem (1990) 33: 3176-3181 [PMID:2258903]
ChEMBL	In vitro displacement of [3H]-LY 278584 from rat cerebral cortex 5-hydroxytryptamine 3 receptor	B	8.89	pKi	1.28	nM	Ki	Bioorg Med Chem Lett (1996) 6: 1195-1198
ChEMBL	Binding affinity to 5-hydroxytryptamine 3 receptor using [3H]quipazine as radioligand in rat cortex	B	9.22	pKi	0.6	nM	Ki	J Med Chem (1990) 33: 1594-1600 [PMID:2342053]
ChEMBL	Inhibition of [3H]GR-65630 binding to rat cortical membrane serotonin 3 receptor	B	8.51	pIC50	3.1	nM	IC50	Bioorg Med Chem Lett (1994) 4: 695-698
ChEMBL	Binding affinity was evaluated in vitro by displacement of [3H]zacopride radioligand from 5-hydroxytryptamine 3 receptor	B	8.64	pIC50	2.3	nM	IC50	Bioorg Med Chem Lett (1992) 2: 245-248
ChEMBL	Inhibition of 5-HT (1 ug/mL) induced depolarization in rat vagus nerve (5-hydroxytryptamine 3 receptor antagonism)	F	8.85	pIC50	1.4	nM	IC50	Bioorg Med Chem Lett (1994) 4: 695-698
ChEMBL	Compound was evaluated for the displacement of [3H]Q-ICS-205-930 from 5-HT3 recognition sites in rat brain membranes	B	8.9	pIC50	1.26	nM	IC50	J Med Chem (1992) 35: 1019-1031 [PMID:1552497]
5-HT3A/Serotonin 3a (5-HT3a) receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1899] [GtoPdb: 373] [UniProtKB: P46098]
ChEMBL	Inhibition of 5HT3 receptor	B	8.28	pKi	5.3	nM	Ki	J Med Chem (2011) 54: 7943-7961 [PMID:21919481]
ChEMBL	Binding affinity at 5HT3 receptor	B	8.55	pKi	2.82	nM	Ki	Bioorg Med Chem (2009) 17: 2607-2622 [PMID:19261477]
ChEMBL	Binding affinity towards 5-hydroxytryptamine 3 receptor by displacement of [3H]2 in Neuroblastoma-Glioma NG-108-15 cells	B	8.57	pKi	2.7	nM	Ki	J Med Chem (1990) 33: 2715-2720 [PMID:2213824]
ChEMBL	In vitro binding affinity for the 5-hydroxytryptamine 3 receptor was determined with NG-108-15 mouse neuroblastoma-glioma cells	B	8.57	pKi	2.7	nM	Ki	J Med Chem (1990) 33: 2721-2725 [PMID:2145434]
Serotonin 3a (5-HT3a) receptor in Guinea pig (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3666] [UniProtKB: O70212]
ChEMBL	Antagonist activity at 5HT3 receptor in spontaneously beating guinea pig right atrium assessed as inhibition of serotonin-induced maximum response by competitive binding assay	B	7.52	pKd	30.2	nM	Kd	J Med Chem (2009) 52: 3548-3562 [PMID:19425598]
5-HT4 receptor/Serotonin 4 (5-HT4) receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1875] [GtoPdb: 9] [UniProtKB: Q13639]
ChEMBL	Binding affinity at 5HT4 receptor	B	6.7	pKi	199.53	nM	Ki	Bioorg Med Chem (2009) 17: 2607-2622 [PMID:19261477]
GtoPdb	-	-	7.1	pKi	-	-	-	J Neurochem (1997) 69: 1810-9 [PMID:9349523]; Naunyn Schmiedebergs Arch Pharmacol (2001) 363: 146-60 [PMID:11218067]
5-HT4 receptor/Serotonin 4 (5-HT4) receptor in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2183] [GtoPdb: 9] [UniProtKB: P97288]
ChEMBL	Tested for ability to stimulate 5-hydroxytryptamine 4 receptors in mouse Coliculi neurons	B	6.2	pKi	6.2	nM	Log Ki	J Med Chem (2003) 46: 319-344 [PMID:12540230]
GtoPdb	-	-	7.1	pKi	-	-	-	FEBS Lett (1996) 398: 19-25 [PMID:8946946]
5-HT4 receptor/Serotonin 4 (5-HT4) receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4317] [GtoPdb: 9] [UniProtKB: Q62758]
GtoPdb	-	-	6.8	pKi	-	-	-	Eur J Pharmacol (1996) 304: 231-5 [PMID:8813606]
ChEMBL	Displacement of [3H]GR-113808 from rat striatum 5-hydroxytryptamine 4 receptor	B	7.2	pKi	63	nM	Ki	Bioorg Med Chem Lett (1996) 6: 1195-1198
Serotonin 4 (5-HT4) receptor in Guinea pig (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5017] [UniProtKB: O70528]
ChEMBL	Evaluated for the antagonistic activity against Serotonin 5-hydroxytryptamine 4 receptor in non-electrically stimulated guinea-pig ileum.	F	5.7	pKd	1995.26	nM	Kd	Bioorg Med Chem Lett (1992) 2: 461-466
ChEMBL	Binding affinity towards 5-hydroxytryptamine 4 receptor in striatum membranes of guinea-pig brain was evaluated	B	6.9	pKi	125.1	nM	Ki	Bioorg Med Chem Lett (2002) 12: 189-192 [PMID:11755351]
ChEMBL	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT4 radioligand binding (ligand: [3H] GR-113808)	B	7.27	pKi	54	nM	Ki	DrugMatrix in vitro pharmacology data
ChEMBL	Inhibition of 5-HT-evoked 5-HT4 receptor-mediated contractions in the guinea pig distal colon longitudinal muscle myenteric plexus (LMMP)	F	5.5	pIC50	3162.28	nM	IC50	J Med Chem (1993) 36: 4121-4123 [PMID:8258837]
ChEMBL	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT4 radioligand binding (ligand: [3H] GR-113808)	B	6.49	pIC50	324	nM	IC50	DrugMatrix in vitro pharmacology data
SERT/Serotonin transporter in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL228] [GtoPdb: 928] [UniProtKB: P31645]
ChEMBL	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	B	6.59	pKi	259	nM	Ki	DrugMatrix in vitro pharmacology data
ChEMBL	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	B	6.31	pIC50	488	nM	IC50	DrugMatrix in vitro pharmacology data
5-HT3A in Human [GtoPdb: 379]
GtoPdb	-	-	8.8	pKi	1.5	nM	Ki	Mol Pharmacol (1995) 48: 407-16 [PMID:7565620]; Mol Pharmacol (1998) 53: 202-12 [PMID:9463477]
glycine receptor α1 subunit in Human [GtoPdb: 423] [UniProtKB: P23415]
GtoPdb	-	-	4.1	pKi	84000	nM	Ki
glycine receptor α2 subunit in Human [GtoPdb: 424] [UniProtKB: P23416]
GtoPdb	-	-	4.9	pKi	13000	nM	Ki
glycine receptor β subunit in Human [GtoPdb: 427] [UniProtKB: P48167]
GtoPdb	-	-	5.3	pKi	5400	nM	Ki
Glycine Receptor (All subtypes) in Human [GtoPdb: 428]
GtoPdb	-	-	4.1	pIC50	-	-	-	J Neurochem (1999) 73: 802-6 [PMID:10428078]; J Neurochem (2007) 100: 758-69 [PMID:17181559]

ChEMBL data shown on this page come from version 32:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]