ChEMBL ligand: CHEMBL559569 (SB-612111)
δ receptor/Delta opioid receptor in Human [ChEMBL: CHEMBL236] [GtoPdb: 317] [UniProtKB: P41143] There should be some charts here, you may need to enable JavaScript!
κ receptor/Kappa opioid receptor in Human [ChEMBL: CHEMBL237] [GtoPdb: 318] [UniProtKB: P41145] There should be some charts here, you may need to enable JavaScript!
μ receptor/Mu opioid receptor in Human [ChEMBL: CHEMBL233] [GtoPdb: 319] [UniProtKB: P35372] There should be some charts here, you may need to enable JavaScript!
NOP receptor/Nociceptin receptor in Human [ChEMBL: CHEMBL2014] [GtoPdb: 320] [UniProtKB: P41146] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
δ receptor/Delta opioid receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL236] [GtoPdb: 317] [UniProtKB: P41143]
ChEMBL	Displacement of [3H]diprenorphine from human cloned delta type opioid receptor expressed in CHO cell membranes by scintillation counter	B	6.4	pKi	>400	nM	Ki	J Med Chem (2012) 55: 4955-4967 [PMID:22541041]
κ receptor/Kappa opioid receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL237] [GtoPdb: 318] [UniProtKB: P41145]
ChEMBL	Displacement of [3H]diprenorphine from human cloned kappa type opioid receptor expressed in CHO cell membranes by scintillation counter	B	6.4	pKi	>400	nM	Ki	J Med Chem (2012) 55: 4955-4967 [PMID:22541041]
μ receptor/Mu opioid receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL233] [GtoPdb: 319] [UniProtKB: P35372]
ChEMBL	Displacement of [3H]diprenorphine from human cloned mu type opioid receptor expressed in CHO cell membranes by scintillation counter	B	6.4	pKi	>400	nM	Ki	J Med Chem (2012) 55: 4955-4967 [PMID:22541041]
ChEMBL	Displacement of [3H]DAMGO from recombinant human mu opioid receptor expressed in CHO cell membranes after 60 mins by scintillation counting method	B	7.24	pKi	58	nM	Ki	J Med Chem (2016) 59: 7011-7028 [PMID:26878436]
NOP receptor/Nociceptin receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2014] [GtoPdb: 320] [UniProtKB: P41146]
ChEMBL	Displacement of [3H]nociceptin from recombinant human nociceptin opioid receptor expressed in CHO cell membranes after 60 mins by scintillation counting method	B	9.48	pKi	0.33	nM	Ki	J Med Chem (2016) 59: 7011-7028 [PMID:26878436]
GtoPdb	-	-	9.5	pKi	-	-	-	J Pharmacol Exp Ther (2004) 308: 454-61 [PMID:14593080]; J Pharmacol Exp Ther (2007) 321: 961-7 [PMID:17329552]
ChEMBL	Displacement of [3H]Nociceptin from human recombinant NOP receptor expressed in CHO cells by scintillation counter	B	9.6	pKi	0.25	nM	Ki	J Med Chem (2012) 55: 4955-4967 [PMID:22541041]
ChEMBL	Displacement of [3H]nociceptin from human recombinant NOP receptor expressed in CHO cells after 60 mins by microbeta scintillation counting	B	9.6	pKi	0.25	nM	Ki	J Med Chem (2011) 54: 2687-2700 [PMID:21438532]
GtoPdb	-	-	9.7	pIC50	-	-	-	J Pharmacol Exp Ther (2004) 308: 454-61 [PMID:14593080]; J Pharmacol Exp Ther (2007) 321: 961-7 [PMID:17329552]

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]