deltorphin II [Ligand Id: 1615] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL29078 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| δ receptor in Human [GtoPdb: 317] [UniProtKB: P41143] | ||||||||
| GtoPdb | - | - | 8.8 | pKi | - | - | - | NIDA Res Monogr (1998) 178: 440-66 [PMID:9686407] |
| δ receptor/Delta opioid receptor in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3222] [GtoPdb: 317] [UniProtKB: P32300] | ||||||||
| GtoPdb | - | - | 8.5 | pKi | - | - | - | Mol Pharmacol (1994) 45: 330-4 [PMID:8114680] |
| ChEMBL | In vitro opioid receptor delta mediated mouse vas deferens (MVD) assay | B | 9.12 | pIC50 | 0.75 | nM | IC50 | J Med Chem (1991) 34: 1656-1661 [PMID:1851843] |
| δ receptor/Delta opioid receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL269] [GtoPdb: 317] [UniProtKB: P33533] | ||||||||
| ChEMBL | Displacement of [3H]DSLET from delta opioid receptor in rat brain membrane | B | 8.42 | pIC50 | 3.8 | nM | IC50 | J Med Chem (1991) 34: 1656-1661 [PMID:1851843] |
| ChEMBL | Displacement of [3H]- DPDPE from delta opioid receptor in rat brain membrane | B | 8.44 | pIC50 | 3.6 | nM | IC50 | J Med Chem (1991) 34: 1656-1661 [PMID:1851843] |
| μ receptor/Mu opioid receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL270] [GtoPdb: 319] [UniProtKB: P33535] | ||||||||
| ChEMBL | Displacement of [3H]- DAGO from opioid receptor mu in rat brain membrane | B | 5.49 | pIC50 | 3200 | nM | IC50 | J Med Chem (1991) 34: 1656-1661 [PMID:1851843] |
| Mu opioid receptor in Guinea pig (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4354] [UniProtKB: P97266] | ||||||||
| ChEMBL | Inhibition of opioid receptor mu in guinea pig ileum (GPI) | B | 5.28 | pIC50 | 5200 | nM | IC50 | J Med Chem (1991) 34: 1656-1661 [PMID:1851843] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
