NPY [Ligand Id: 1505] activity data from GtoPdb

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  • Y1 receptor in Human [GtoPdb: 305] [UniProtKB: P25929]
  • Y1 receptor in Rat [GtoPdb: 305] [UniProtKB: P21555]
Created with Highcharts 10.3.3ValuesChart context menuY1 receptorpKd HumanpKi HumanpIC50 HumanpEC50 HumanpKd RatpKi RatpIC50 RatpEC50 Rat024681012Highcharts.com
  • Y2 receptor in Human [GtoPdb: 306] [UniProtKB: P49146]
Created with Highcharts 10.3.3ValuesChart context menuY2 receptorpKd HumanpKi HumanpIC50 HumanpEC50 Human0246810Highcharts.com
  • Y4 receptor in Rat [GtoPdb: 307] [UniProtKB: Q63447]
Created with Highcharts 10.3.3ValuesChart context menuY4 receptorpKd RatpKi RatpIC50 RatpEC50 Rat0246810Highcharts.com
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Y1 receptor in Human [GtoPdb: 305] [UniProtKB: P25929]
GtoPdb - - 9.7 pKi - - - Biochem J (2006) 393: 161-9 [PMID:16097949]
Y1 receptor in Rat [GtoPdb: 305] [UniProtKB: P21555]
GtoPdb - - 10 pKi - - - Peptides (1997) 18: 397-401 [PMID:9145427]
Y2 receptor in Human [GtoPdb: 306] [UniProtKB: P49146]
GtoPdb - - 9.3 pKi - - - Mol Pharmacol (1996) 49: 224-8 [PMID:8632753];
J Biol Chem (1995) 270: 26758-61 [PMID:7592910]
Y4 receptor in Rat [GtoPdb: 307] [UniProtKB: Q63447]
GtoPdb - - 8.7 pKi - - - Peptides (1997) 18: 397-401 [PMID:9145427]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.