TYK2 inhibitor 18 [WO2023227946] [Ligand Id: 13429] activity data from GtoPdb

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  • tyrosine kinase 2 in Human [GtoPdb: 2269] [UniProtKB: P29597]
Created with Highcharts 10.3.3ValuesChart context menutyrosine kinase 2pKd HumanpKi HumanpIC50 HumanpEC50 Human02468Highcharts.com
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
tyrosine kinase 2 in Human [GtoPdb: 2269] [UniProtKB: P29597]
GtoPdb Inhibition of TYK2-mediated induction of IL-23 and IFNα production in cellular reporter gene assays. - 7.52 pIC50 <30 nM IC50 WO2023227946A1. Tyk2 inhibitors and uses thereof (2023)

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.