MS8535 [Ligand Id: 13299] activity data from GtoPdb

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  • spindlin 1 in Human [GtoPdb: 3274] [UniProtKB: Q9Y657]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
spindlin 1 in Human [GtoPdb: 3274] [UniProtKB: Q9Y657]
GtoPdb Binding affinity determined in an ITC assay - 7.52 pKd 30 nM Kd J Med Chem (2024) 67: 5837-5853 [PMID:38533580]
GtoPdb Inhibitor potency in a fluorescence polarisation assay - 6.69 pIC50 202 nM IC50 J Med Chem (2024) 67: 5837-5853 [PMID:38533580]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.