zurletrectinib [Ligand Id: 12389] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| neurotrophic receptor tyrosine kinase 1 in Human [GtoPdb: 1817] [UniProtKB: P04629] | ||||||||
| GtoPdb | - | - | 9.09 | pIC50 | 0.81 | nM | IC50 | Br J Cancer (2024) 131: 601-610 [PMID:38902532] |
| GtoPdb | - | - | 9.62 | pIC50 | 0.24 | nM | IC50 | US20210147445A1. Heterocyclic compound as trk inhibitor (2021) |
| neurotrophic receptor tyrosine kinase 2 in Human [GtoPdb: 1818] [UniProtKB: Q16620] | ||||||||
| GtoPdb | - | - | 9.84 | pIC50 | 0.14 | nM | IC50 | Br J Cancer (2024) 131: 601-610 [PMID:38902532] |
| neurotrophic receptor tyrosine kinase 3 in Human [GtoPdb: 1819] [UniProtKB: Q16288] | ||||||||
| GtoPdb | - | - | 9.74 | pIC50 | 0.18 | nM | IC50 | Br J Cancer (2024) 131: 601-610 [PMID:38902532] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
