chiglitazar [Ligand Id: 12287] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL4650349 (Carfloglitazar, (s)-, Chiglitazar, CS 038, CS-038) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| Peroxisome proliferator-activated receptor-α in Human [GtoPdb: 593] [UniProtKB: Q07869] | ||||||||
| GtoPdb | Measuring transactivation by human PPARα in U-2OS cells | - | 5.92 | pEC50 | 1200 | nM | EC50 | Br J Pharmacol (2006) 148: 610-8 [PMID:16751799] |
| Peroxisome proliferator-activated receptor-γ in Human [GtoPdb: 595] [UniProtKB: P37231] | ||||||||
| GtoPdb | Measuring transactivation by human PPARδ in U-2OS cells | - | 7.1 | pEC50 | 80 | nM | EC50 | Br J Pharmacol (2006) 148: 610-8 [PMID:16751799] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
