ChEMBL ligand: CHEMBL4594280 (DKFZ-PSMA-617, PSMA-617, PSMA617, Vipivotida tetraxetan, Vipivotide tetraxetan)
Folate hydrolase (prostate-specific membrane antigen) 1/Glutamate carboxypeptidase II in Human [ChEMBL: CHEMBL1892] [GtoPdb: 1606] [UniProtKB: Q04609] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
Folate hydrolase (prostate-specific membrane antigen) 1/Glutamate carboxypeptidase II in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1892] [GtoPdb: 1606] [UniProtKB: Q04609]
ChEMBL	Binding affinity to PSMA in human LNCaP cells after 45 mins in presence of 68Ga-labeled PSMA-10 by gamma counting assay	B	8.63	pKi	2.34	nM	Ki	J Med Chem (2016) 59: 1761-1775 [PMID:26878194]
GtoPdb	Inhibition of PSMA enzymatic activity	-	9.43	pKi	0.37	nM	Ki	J Nucl Med (2015) 56: 914-20 [PMID:25883127]
ChEMBL	Displacement of [125I]MIP-1095 from PSMA in human PC3-PIP cells after 1 hr by gamma counter analysis	B	7.96	pIC50	10.9	nM	IC50	Bioorg Med Chem (2020) 28: 115319-115319 [PMID:32001090]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]