BAY-545 [Ligand Id: 11224] activity data from GtoPdb

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  • A2B receptor in Human [GtoPdb: 20] [UniProtKB: P29275]
  • A2B receptor in Mouse [GtoPdb: 20] [UniProtKB: Q60614]
  • A2B receptor in Rat [GtoPdb: 20] [UniProtKB: P29276]
Created with Highcharts 10.3.3ValuesChart context menuA2B receptorpKd HumanpKi HumanpIC50 HumanpEC50 HumanpKd MousepKi MousepIC50 MousepEC50 MousepKd RatpKi RatpIC50 RatpEC50 Rat02468Highcharts.com
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
A2B receptor in Human [GtoPdb: 20] [UniProtKB: P29275]
GtoPdb - - 7.01 pKi 97 nM Ki Eur J Med Chem (2019) 163: 763-778 [PMID:30576906]
A2B receptor in Mouse [GtoPdb: 20] [UniProtKB: Q60614]
GtoPdb - - 6.4 pIC50 400 nM IC50 Eur J Med Chem (2019) 163: 763-778 [PMID:30576906]
A2B receptor in Rat [GtoPdb: 20] [UniProtKB: P29276]
GtoPdb - - 6.55 pIC50 280 nM IC50 Eur J Med Chem (2019) 163: 763-778 [PMID:30576906]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.