imaradenant [Ligand Id: 11153] activity data from GtoPdb

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  • A1 receptor in Human [GtoPdb: 18] [UniProtKB: P30542]
Created with Highcharts 10.3.3ValuesChart context menuA1 receptorpKd HumanpKi HumanpIC50 HumanpEC50 Human02468Highcharts.com
  • A2A receptor in Human [GtoPdb: 19] [UniProtKB: P29274]
Created with Highcharts 10.3.3ValuesChart context menuA2A receptorpKd HumanpKi HumanpIC50 HumanpEC50 Human0246810Highcharts.com
  • A2B receptor in Human [GtoPdb: 20] [UniProtKB: P29275]
Created with Highcharts 10.3.3ValuesChart context menuA2B receptorpKd HumanpKi HumanpIC50 HumanpEC50 Human02468Highcharts.com
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
A1 receptor in Human [GtoPdb: 18] [UniProtKB: P30542]
GtoPdb Binding affinity of AZD4635 determined in a radioligand binding competition assays with membranes prepared from CHO cells stably expressing human A1R. - 6.8 pKi 160 nM Ki J Immunother Cancer (2020) 8: e000417 [PMID:32727810]
A2A receptor in Human [GtoPdb: 19] [UniProtKB: P29274]
GtoPdb Binding affinity of AZD4635 determined in a radioligand binding competition assays with membranes prepared from HEK-293-T cells stably expressing human A2AR. - 8.77 pKi 1.7 nM Ki J Immunother Cancer (2020) 8: e000417 [PMID:32727810]
A2B receptor in Human [GtoPdb: 20] [UniProtKB: P29275]
GtoPdb Binding affinity of AZD4635 determined in a radioligand binding competition assays with membranes prepared from HEK-293-T cells stably expressing human A2BR. - 7.19 pKi 64 nM Ki J Immunother Cancer (2020) 8: e000417 [PMID:32727810]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.