NIK inhibitor 12f [Ligand Id: 10947] activity data from GtoPdb
Click here for a description of the charts and data table
Please tell us if you are using this feature and what you think!
|
There should be some charts here, you may need to enable JavaScript!
|
|
There should be some charts here, you may need to enable JavaScript!
|
|
There should be some charts here, you may need to enable JavaScript!
|
|
There should be some charts here, you may need to enable JavaScript!
|
|
There should be some charts here, you may need to enable JavaScript!
|
|
There should be some charts here, you may need to enable JavaScript!
|
|
There should be some charts here, you may need to enable JavaScript!
|
| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| neurotrophic receptor tyrosine kinase 3 in Human [GtoPdb: 1819] [UniProtKB: Q16288] | ||||||||
| GtoPdb | Inhibitory concentration determined in a Reaction Biology kinase sreening assay. | - | 7.3 | pIC50 | 50.1 | nM | IC50 | J Med Chem (2020) 63: 6748-6773 [PMID:32479083] |
| aurora kinase B in Human [GtoPdb: 1937] [UniProtKB: Q96GD4] | ||||||||
| GtoPdb | Inhibitory concentration determined in a Reaction Biology kinase sreening assay. | - | 7.36 | pIC50 | 43.2 | nM | IC50 | J Med Chem (2020) 63: 6748-6773 [PMID:32479083] |
| Janus kinase 1 in Human [GtoPdb: 2047] [UniProtKB: P23458] | ||||||||
| GtoPdb | Inhibitory concentration determined in a Reaction Biology kinase sreening assay. | - | 6.74 | pIC50 | 182.6 | nM | IC50 | J Med Chem (2020) 63: 6748-6773 [PMID:32479083] |
| Janus kinase 3 in Human [GtoPdb: 2049] [UniProtKB: P52333] | ||||||||
| GtoPdb | Inhibitory concentration determined in a Reaction Biology kinase sreening assay. | - | 6.05 | pIC50 | 892 | nM | IC50 | J Med Chem (2020) 63: 6748-6773 [PMID:32479083] |
| leucine rich repeat kinase 2 in Human [GtoPdb: 2059] [UniProtKB: Q5S007] | ||||||||
| GtoPdb | Inhibitory concentration determined in a Reaction Biology kinase sreening assay. | - | 7.02 | pIC50 | 94.6 | nM | IC50 | J Med Chem (2020) 63: 6748-6773 [PMID:32479083] |
| mitogen-activated protein kinase kinase kinase 14 in Human [GtoPdb: 2074] [UniProtKB: Q99558] | ||||||||
| GtoPdb | Inhibition of enzyme activity in a biochemical assay. | - | 8.01 | pIC50 | 9.87 | nM | IC50 | J Med Chem (2020) 63: 6748-6773 [PMID:32479083] |
| tyrosine kinase non receptor 2 in Human [GtoPdb: 2246] [UniProtKB: Q07912] | ||||||||
| GtoPdb | Inhibitory concentration determined in a Reaction Biology kinase sreening assay. | - | 6.72 | pIC50 | 191.7 | nM | IC50 | J Med Chem (2020) 63: 6748-6773 [PMID:32479083] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
