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ChEMBL ligand: CHEMBL2365410 |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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calpain 1 in Human [GtoPdb: 2336] [UniProtKB: P07384] | ||||||||
GtoPdb | - | - | 7.13 | pIC50 | 74 | nM | IC50 | ACS Pharmacol Transl Sci (2021) 4: 1408-1421 [PMID:34414360] |
cathepsin K in Human [GtoPdb: 2350] [UniProtKB: P43235] | ||||||||
GtoPdb | - | - | 7.59 | pIC50 | 26 | nM | IC50 | ACS Pharmacol Transl Sci (2021) 4: 1408-1421 [PMID:34414360] |
cathepsin L in Human [GtoPdb: 2351] [UniProtKB: P07711] | ||||||||
GtoPdb | - | - | 8.36 | pIC50 | 4.4 | nM | IC50 | ACS Pharmacol Transl Sci (2021) 4: 1408-1421 [PMID:34414360] |
CoV 3C-like (main) protease in SARS-CoV [GtoPdb: 3111] [UniProtKB: P0C6U8] | ||||||||
GtoPdb | - | - | 7.3 | pIC50 | 50 | nM | IC50 | Nat Commun (2020) 11: 4282 [PMID:32855413] |
GtoPdb | - | - | 7.39 | pIC50 | 41 | nM | IC50 | ACS Pharmacol Transl Sci (2021) 4: 1408-1421 [PMID:34414360] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]