ChEMBL ligand: CHEMBL82293 (Cetyl acid, Cetylic acid, FEMA NO. 2832, IMEX C 1498, KORTACID 1698, LOXIOL EP 278, N-hexadecanoic acid, NSC-5030, Palmitate, Palmitic acid, Prifac-2960, Pristerene-4934)
Acetylcholinesterase in Electrophorus electricus [ChEMBL: CHEMBL4078] [UniProtKB: O42275] There should be some charts here, you may need to enable JavaScript!
fatty acid binding protein 4/Fatty acid binding protein adipocyte in Human [ChEMBL: CHEMBL2083] [GtoPdb: 2534] [UniProtKB: P15090] There should be some charts here, you may need to enable JavaScript!
fatty acid binding protein 5/Fatty acid binding protein epidermal in Human [ChEMBL: CHEMBL3674] [GtoPdb: 2535] [UniProtKB: Q01469] There should be some charts here, you may need to enable JavaScript!
fatty acid binding protein 2/Fatty acid binding protein intestinal in Human [ChEMBL: CHEMBL4879] [GtoPdb: 2532] [UniProtKB: P12104] There should be some charts here, you may need to enable JavaScript!
fatty acid binding protein 3/Fatty acid binding protein muscle in Human [ChEMBL: CHEMBL3344] [GtoPdb: 2533] [UniProtKB: P05413] There should be some charts here, you may need to enable JavaScript!
Olfactory receptor 51E2 in Human [ChEMBL: CHEMBL4523454] [UniProtKB: Q9H255] There should be some charts here, you may need to enable JavaScript!
Peroxisome proliferator-activated receptor-α/Peroxisome proliferator-activated receptor alpha in Human [ChEMBL: CHEMBL239] [GtoPdb: 593] [UniProtKB: Q07869] There should be some charts here, you may need to enable JavaScript!
Peroxisome proliferator-activated receptor-β/δ/Peroxisome proliferator-activated receptor delta in Human [ChEMBL: CHEMBL3979] [GtoPdb: 594] [UniProtKB: Q03181] There should be some charts here, you may need to enable JavaScript!
Peroxisome proliferator-activated receptor-γ/Peroxisome proliferator-activated receptor gamma in Human [ChEMBL: CHEMBL235] [GtoPdb: 595] [UniProtKB: P37231] There should be some charts here, you may need to enable JavaScript!
protein tyrosine phosphatase non-receptor type 1/Protein-tyrosine phosphatase 1B in Human [ChEMBL: CHEMBL335] [GtoPdb: 2976] [UniProtKB: P18031] There should be some charts here, you may need to enable JavaScript!
TLR2/Toll-like receptor 2 in Human [ChEMBL: CHEMBL4163] [GtoPdb: 1752] [UniProtKB: O60603] There should be some charts here, you may need to enable JavaScript!
TRPV2/Transient receptor potential cation channel subfamily V member 2 in Rat [ChEMBL: CHEMBL2863] [GtoPdb: 508] [UniProtKB: Q9WUD2] There should be some charts here, you may need to enable JavaScript!
FFA1 receptor in Human [GtoPdb: 225] [UniProtKB: O14842] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
Acetylcholinesterase in Electrophorus electricus (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4078] [UniProtKB: O42275]
ChEMBL	Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured at 1 min intervals for 30 mins by Ellman's method	B	4.99	pIC50	10150	nM	IC50	Bioorg Med Chem Lett (2018) 28: 3315-3319 [PMID:30220607]
fatty acid binding protein 4/Fatty acid binding protein adipocyte in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2083] [GtoPdb: 2534] [UniProtKB: P15090]
ChEMBL	Binding affinity against Adipocyte lipid binding protein	B	4.08	pKd	83000	nM	Kd	J Med Chem (2002) 45: 2469-2483 [PMID:12036355]
ChEMBL	Displacement of 1,8-ANS from aFABP by fluorescence based-assay	B	6.47	pKi	336	nM	Ki	Bioorg Med Chem Lett (2007) 17: 3511-3515 [PMID:17502136]
ChEMBL	In vitro inhibitory concentration against adipocyte fatty acid binding protein(A-FABP)	B	6.03	pIC50	930	nM	IC50	Bioorg Med Chem Lett (2004) 14: 4445-4448 [PMID:15357969]
ChEMBL	Inhibition of FABP4 (unknown origin) by fluorescence polarization assay	B	6.03	pIC50	930	nM	IC50	Eur J Med Chem (2017) 138: 854-873 [PMID:28738306]
fatty acid binding protein 5/Fatty acid binding protein epidermal in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3674] [GtoPdb: 2535] [UniProtKB: Q01469]
ChEMBL	Binding affinity to human kFABP	B	6.1	pKd	802	nM	Kd	J Med Chem (2006) 49: 5013-5017 [PMID:16884313]
ChEMBL	Displacement of 1,8-ANS from eFABP by fluorescence based-assay	B	6.1	pKi	802	nM	Ki	Bioorg Med Chem Lett (2007) 17: 3511-3515 [PMID:17502136]
ChEMBL	In vitro inhibitory concentration against epithelial fatty acid binding protein(E-FABP)	B	5.92	pIC50	1200	nM	IC50	Bioorg Med Chem Lett (2004) 14: 4445-4448 [PMID:15357969]
ChEMBL	Inhibition of FABP5 (unknown origin) by fluorescence polarization assay	B	5.92	pIC50	1200	nM	IC50	Eur J Med Chem (2017) 138: 854-873 [PMID:28738306]
fatty acid binding protein 2/Fatty acid binding protein intestinal in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4879] [GtoPdb: 2532] [UniProtKB: P12104]
ChEMBL	Binding affinity against Fatty acid-binding protein	B	5.43	pKd	-5.43	-	Log Kd	J Med Chem (2002) 45: 2770-2780 [PMID:12061879]
ChEMBL	In vitro inhibitory concentration against intestinal fatty acid binding protein(I-FABP)	B	5.77	pIC50	1700	nM	IC50	Bioorg Med Chem Lett (2004) 14: 4445-4448 [PMID:15357969]
fatty acid binding protein 3/Fatty acid binding protein muscle in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3344] [GtoPdb: 2533] [UniProtKB: P05413]
ChEMBL	In vitro inhibitory concentration against heart and muscle fatty acid binding protein(H-FABP)	B	5.59	pIC50	2600	nM	IC50	Bioorg Med Chem Lett (2004) 14: 4445-4448 [PMID:15357969]
ChEMBL	Inhibition of FABP3 (unknown origin) by fluorescence polarization assay	B	5.59	pIC50	2600	nM	IC50	Eur J Med Chem (2017) 138: 854-873 [PMID:28738306]
Olfactory receptor 51E2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4523454] [UniProtKB: Q9H255]
ChEMBL	Agonist activity at PSGR/OR51E2 (unknown origin) expressed in human Hana3A cells co-transfected with CRE-Luc by luciferase reporter gene assay	F	8.01	pEC50	9.8	nM	EC50	US-20180116992-A1. Modulators of Prostate-Specific G-Protein Receptor (PSGR/OR51E2) and Methods of Using Same (2018)
Peroxisome proliferator-activated receptor-α/Peroxisome proliferator-activated receptor alpha in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL239] [GtoPdb: 593] [UniProtKB: Q07869]
ChEMBL	Displacement of [3H]GW2331 from Homo sapiens (human) PPARalpha receptor by scintillation proximity assay	B	5.82	pIC50	1500	nM	IC50	Med Chem Res (2013) 22: 3126-3133
ChEMBL	Agonist activity at recombinant human PPARalpha LBD (168 to 468 residues) expressed in African green monkey COS-1 cells incubated for 18 hrs by luciferase reporter gene assay	B	4.46	pEC50	35000	nM	EC50	Eur J Med Chem (2018) 155: 736-753 [PMID:29940464]
Peroxisome proliferator-activated receptor-β/δ/Peroxisome proliferator-activated receptor delta in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3979] [GtoPdb: 594] [UniProtKB: Q03181]
ChEMBL	Displacement of [3H]GW2433 from Homo sapiens (human) PPARdelta receptor by scintillation proximity assay	B	5.13	pIC50	7400	nM	IC50	Med Chem Res (2013) 22: 3126-3133
Peroxisome proliferator-activated receptor-γ/Peroxisome proliferator-activated receptor gamma in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL235] [GtoPdb: 595] [UniProtKB: P37231]
ChEMBL	Displacement of [3H]BRL49653 from Homo sapiens (human) PPARgamma receptor by scintillation proximity assay	B	4.52	pIC50	30000	nM	IC50	Med Chem Res (2013) 22: 3126-3133
protein tyrosine phosphatase non-receptor type 1/Protein-tyrosine phosphatase 1B in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL335] [GtoPdb: 2976] [UniProtKB: P18031]
ChEMBL	Inhibition of PTP1B (unknown origin) using pNPP as substrate incubated for 30 mins by photometric method	B	5.06	pIC50	8800	nM	IC50	J Nat Prod (2020) 83: 1598-1610 [PMID:32255628]
TLR2/Toll-like receptor 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4163] [GtoPdb: 1752] [UniProtKB: O60603]
ChEMBL	Inhibition of TLR2 agonist Pam3Cys-Ser-(Lys)4-OH-mediated IL8 secretion in THP1 cells	F	5.3	pIC50	5000	nM	IC50	J Med Chem (2006) 49: 1754-1765 [PMID:16509590]
TRPV2/Transient receptor potential cation channel subfamily V member 2 in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2863] [GtoPdb: 508] [UniProtKB: Q9WUD2]
ChEMBL	Antagonist activity at recombinant rat TRPV2 expressed in HEK293 cells assessed as inhibition of LPC-induced Ca2+ levels preincubated for 5 mins followed by agonist addition by Fuo-4-AM based spectrofluorimetry	B	5	pIC50	>10000	nM	IC50	J Med Chem (2018) 61: 8255-8281 [PMID:30176215]
ChEMBL	Antagonist activity at recombinant rat TRPV2 expressed in HEK293 cells assessed as inhibition of CBD-induced Ca2+ levels preincubated for 5 mins followed by agonist addition by Fuo-4-AM based spectrofluorimetry	B	5	pIC50	>10000	nM	IC50	J Med Chem (2018) 61: 8255-8281 [PMID:30176215]
FFA1 receptor in Human [GtoPdb: 225] [UniProtKB: O14842]
GtoPdb	-	-	5.3	pEC50	-	-	-	J Biol Chem (2003) 278: 11303-11 [PMID:12496284]; Biochem Biophys Res Commun (2003) 301: 406-10 [PMID:12565875]; Nature (2003) 422: 173-6 [PMID:12629551]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]