Lys01 [Ligand Id: 10320] activity data from GtoPdb and ChEMBL

Click here for a description of the charts and data table

Please tell us if you are using this feature and what you think!

ChEMBL ligand: CHEMBL4282488
  • Plasmodium falciparum [ChEMBL: CHEMBL364]
  • This target only has 0 pki data point
  • 0
1 CHEMBL4282488_lig_chart_1 Plasmodium falciparum Plasmodium falciparum
There should be some charts here, you may need to enable JavaScript!
  • Plasmodium falciparum heme detoxification protein in Plasmodium falciparum FCR3 [GtoPdb: 3079]
  • Plasmodium falciparum heme detoxification protein in Plasmodium falciparum K1 [GtoPdb: 3079]
  • This target only has 0 pki data point
  • 0
2 CHEMBL4282488_lig_chart_2 Plasmodium falciparum heme detoxification protein Plasmodium falciparum FCR3Plasmodium falciparum K1
There should be some charts here, you may need to enable JavaScript!
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Plasmodium falciparum (target type: ORGANISM) [ChEMBL: CHEMBL364]
ChEMBL Antiplasmodial activity against chloroquine-resistant Plasmodium falciparum K1 infected in human erythrocytes measured after 72 hrs by malstat reagent based LDH release assay F 7.35 pIC50 45 nM IC50 ACS Med Chem Lett (2018) 9: 980-985 [PMID:30344903]
ChEMBL Antiplasmodial activity against chloroquine-sensitive Plasmodium falciparum FCR-3 infected in human erythrocytes measured after 72 hrs by malstat reagent based LDH release assay F 7.7 pIC50 20 nM IC50 ACS Med Chem Lett (2018) 9: 980-985 [PMID:30344903]
Plasmodium falciparum heme detoxification protein in Plasmodium falciparum FCR3 [GtoPdb: 3079]
GtoPdb Parasite growth inhibition assay - 7.7 pIC50 20 nM IC50 ACS Med Chem Lett (2018) 9: 980-985 [PMID:30344903]
Plasmodium falciparum heme detoxification protein in Plasmodium falciparum K1 [GtoPdb: 3079]
GtoPdb Parasite growth inhibition assay - 7.35 pIC50 45 nM IC50 ACS Med Chem Lett (2018) 9: 980-985 [PMID:30344903]

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]