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ChEMBL ligand: CHEMBL4282488 |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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Plasmodium falciparum (target type: ORGANISM) [ChEMBL: CHEMBL364] | ||||||||
ChEMBL | Antiplasmodial activity against chloroquine-resistant Plasmodium falciparum K1 infected in human erythrocytes measured after 72 hrs by malstat reagent based LDH release assay | F | 7.35 | pIC50 | 45 | nM | IC50 | ACS Med Chem Lett (2018) 9: 980-985 [PMID:30344903] |
ChEMBL | Antiplasmodial activity against chloroquine-sensitive Plasmodium falciparum FCR-3 infected in human erythrocytes measured after 72 hrs by malstat reagent based LDH release assay | F | 7.7 | pIC50 | 20 | nM | IC50 | ACS Med Chem Lett (2018) 9: 980-985 [PMID:30344903] |
Plasmodium falciparum heme detoxification protein in Plasmodium falciparum FCR3 [GtoPdb: 3079] | ||||||||
GtoPdb | Parasite growth inhibition assay | - | 7.7 | pIC50 | 20 | nM | IC50 | ACS Med Chem Lett (2018) 9: 980-985 [PMID:30344903] |
Plasmodium falciparum heme detoxification protein in Plasmodium falciparum K1 [GtoPdb: 3079] | ||||||||
GtoPdb | Parasite growth inhibition assay | - | 7.35 | pIC50 | 45 | nM | IC50 | ACS Med Chem Lett (2018) 9: 980-985 [PMID:30344903] |
ChEMBL data shown on this page come from version 31:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]