sutidiazine [Ligand Id: 10024] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL4284447 (Sutidiazina, Sutidiazine) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| Plasmodium falciparum (target type: ORGANISM) [ChEMBL: CHEMBL364] | ||||||||
| ChEMBL | Antimalarial activity against Plasmodium falciparum K1 | F | 7.82 | pIC50 | 15 | nM | IC50 | Eur J Med Chem (2021) 210: 112955-112955 [PMID:33131885] |
| ChEMBL | Antimalarial activity against Plasmodium falciparum NF54 | F | 8.05 | pIC50 | 9 | nM | IC50 | Eur J Med Chem (2021) 210: 112955-112955 [PMID:33131885] |
| ChEMBL | Antimalarial activity against Plasmodium falciparum NF54 after 48 hrs by spectrophotometric analysis | F | 8.3 | pIC50 | 5 | nM | IC50 | Bioorg Med Chem (2023) 88-89: 117339-117339 [PMID:37236020] |
| Plasmodium falciparum V-type proton ATPase subunit D in Plasmodium falciparum K1 [GtoPdb: 3078] | ||||||||
| GtoPdb | Parasite growth inhibition assay | - | 7.82 | pIC50 | 15 | nM | IC50 | Nat Commun (2015) 6: 6715 [PMID:25823686] |
| Plasmodium falciparum V-type proton ATPase subunit D in Plasmodium falciparum NF54 [GtoPdb: 3078] | ||||||||
| GtoPdb | Parasite growth inhibition assay | - | 8.05 | pIC50 | 9 | nM | IC50 | Nat Commun (2015) 6: 6715 [PMID:25823686] |
ChEMBL data shown on this page come from version 35:
Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
