MMV253 [Ligand Id: 10024] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL4284447
  • Plasmodium falciparum V-type proton ATPase subunit D in Plasmodium falciparum K1 [GtoPdb: 3078]
  • Plasmodium falciparum V-type proton ATPase subunit D in Plasmodium falciparum NF54 [GtoPdb: 3078]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Plasmodium falciparum V-type proton ATPase subunit D in Plasmodium falciparum K1 [GtoPdb: 3078]
GtoPdb Parasite growth inhibition assay - 7.82 pIC50 15 nM IC50 Nat Commun (2015) 6: 6715 [PMID:25823686]
Plasmodium falciparum V-type proton ATPase subunit D in Plasmodium falciparum NF54 [GtoPdb: 3078]
GtoPdb Parasite growth inhibition assay - 8.05 pIC50 9 nM IC50 Nat Commun (2015) 6: 6715 [PMID:25823686]

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]