sutidiazine [Ligand Id: 10024] activity data from GtoPdb and ChEMBL

Click here for a description of the charts and data table

Please tell us if you are using this feature and what you think!

ChEMBL ligand: CHEMBL4284447 (Sutidiazina, Sutidiazine)
Created with Highcharts 10.3.3ValuesChart context menuPlasmodium falciparumpKd Plasmodium falciparumpKi Plasmodium falciparumpIC50 Plasmodium falciparumpEC50 Plasmodium falciparum0246810Highcharts.com
  • Plasmodium falciparum V-type proton ATPase subunit D in Plasmodium falciparum K1 [GtoPdb: 3078]
  • Plasmodium falciparum V-type proton ATPase subunit D in Plasmodium falciparum NF54 [GtoPdb: 3078]
Created with Highcharts 10.3.3ValuesChart context menuPlasmodium falciparum V-type proton ATPase subunit DpKd Plasmodium​falciparum K1pKi Plasmodium​falciparum K1pIC50 Plasmodium​falciparum K1pEC50 Plasmodium​falciparum K1pKd Plasmodium​falciparum NF54pKi Plasmodium​falciparum NF54pIC50 Plasmodium​falciparum NF54pEC50 Plasmodium​falciparum NF540246810Highcharts.com
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Plasmodium falciparum (target type: ORGANISM) [ChEMBL: CHEMBL364]
ChEMBL Antimalarial activity against Plasmodium falciparum K1 F 7.82 pIC50 15 nM IC50 Eur J Med Chem (2021) 210: 112955-112955 [PMID:33131885]
ChEMBL Antimalarial activity against Plasmodium falciparum NF54 F 8.05 pIC50 9 nM IC50 Eur J Med Chem (2021) 210: 112955-112955 [PMID:33131885]
ChEMBL Antimalarial activity against Plasmodium falciparum NF54 after 48 hrs by spectrophotometric analysis F 8.3 pIC50 5 nM IC50 Bioorg Med Chem (2023) 88-89: 117339-117339 [PMID:37236020]
Plasmodium falciparum V-type proton ATPase subunit D in Plasmodium falciparum K1 [GtoPdb: 3078]
GtoPdb Parasite growth inhibition assay - 7.82 pIC50 15 nM IC50 Nat Commun (2015) 6: 6715 [PMID:25823686]
Plasmodium falciparum V-type proton ATPase subunit D in Plasmodium falciparum NF54 [GtoPdb: 3078]
GtoPdb Parasite growth inhibition assay - 8.05 pIC50 9 nM IC50 Nat Commun (2015) 6: 6715 [PMID:25823686]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]