NSC 780521 [Ligand Id: 9933] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| dual oxidase 2 in Human [GtoPdb: 2999] [UniProtKB: Q9NRD8] | ||||||||
| GtoPdb | Inhibition of hydrogen peroxide formation in HEK293 cells expressing DUOX2/DUOXA2. | - | 6.11 | pIC50 | 773 | nM | IC50 | Biochem Pharmacol (2017) 143: 25-38 [PMID:28709950] |
| NADPH oxidase 1 in Human [GtoPdb: 3001] [UniProtKB: Q9Y5S8] | ||||||||
| GtoPdb | Inhibition of PMA-induced superoxide production in HEK293 cells expressing hNOX1. | - | 5.99 | pIC50 | 1019 | nM | IC50 | Biochem Pharmacol (2017) 143: 25-38 [PMID:28709950] |
| cytochrome b-245 beta chain in Human [GtoPdb: 3002] [UniProtKB: P04839] | ||||||||
| GtoPdb | Inhibition of PMA-induced superoxide production in human PMNs. | - | 5.98 | pIC50 | 1049 | nM | IC50 | Biochem Pharmacol (2017) 143: 25-38 [PMID:28709950] |
| NADPH oxidase 5 in Human [GtoPdb: 3005] [UniProtKB: Q96PH1] | ||||||||
| GtoPdb | Inhibition of PMA-induced superoxide production by UACC-257 cells. | - | 6.64 | pIC50 | 229 | nM | IC50 | Biochem Pharmacol (2017) 143: 25-38 [PMID:28709950] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
