ChEMBL ligand: CHEMBL2064741
Peroxisome proliferator-activated receptor-γ/Peroxisome proliferator-activated receptor gamma in Human [ChEMBL: CHEMBL235] [GtoPdb: 595] [UniProtKB: P37231] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
Peroxisome proliferator-activated receptor-γ/Peroxisome proliferator-activated receptor gamma in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL235] [GtoPdb: 595] [UniProtKB: P37231]
ChEMBL	Agonist activity at PPARgamma LBD in human 293H DA cells after 16 hrs by TR-FRET activation reporter assay	F	6.33	pEC50	467	nM	EC50	J Med Chem (2012) 55: 4978-4989 [PMID:22582973]
ChEMBL	Binding affinity to PPARgamma LBD by fluorescence polarization based competitive binding assay	B	6.49	pEC50	325	nM	EC50	J Med Chem (2012) 55: 4978-4989 [PMID:22582973]
ChEMBL	Displacement of pan-PPAR fluormone from PPARgamma LBD by TR-FRET based LanthaScreen assay	B	6.67	pEC50	215	nM	EC50	J Med Chem (2012) 55: 4978-4989 [PMID:22582973]
GtoPdb	Measured by TR-FRET analysis.	-	6.67	pEC50	215	nM	EC50	J Med Chem (2012) 55: 4978-89 [PMID:22582973]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]