LUF5962 [Ligand Id: 9813] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL207824 (LUF-5962) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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| A1 receptor/Adenosine receptor A1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL226] [GtoPdb: 18] [UniProtKB: P30542] | ||||||||
| ChEMBL | Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cells | B | 9.54 | pKi | 0.29 | nM | Ki | J Med Chem (2006) 49: 2861-2867 [PMID:16686529] |
| GtoPdb | - | - | 7.13 | pIC50 | - | - | - | Br J Pharmacol (2018) 175: 1719-1730 [PMID:29486053] |
| A2A receptor/Adenosine receptor A2a in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL251] [GtoPdb: 19] [UniProtKB: P29274] | ||||||||
| ChEMBL | Displacement of [3H]ZM 241385 from human adenosine A2a receptor expressed in HEK293 cells | B | 7.26 | pKi | 55 | nM | Ki | J Med Chem (2006) 49: 2861-2867 [PMID:16686529] |
| A3 receptor/Adenosine receptor A3 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL256] [GtoPdb: 21] [UniProtKB: P0DMS8] | ||||||||
| ChEMBL | Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in HEK293 cells | B | 7.46 | pKi | 35 | nM | Ki | J Med Chem (2006) 49: 2861-2867 [PMID:16686529] |
ChEMBL data shown on this page come from version 36:
Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
